Schistosoma mansoni vaccine candidates identified by unbiased phage display screening in self-cured rhesus macaques.
Woellner-Santos D, Tahira AC, Malvezzi JVM, Mesel V, Morales-Vicente DA, Trentini MM, Marques-Neto LM, Matos IA, Kanno AI, Pereira ASA, Teixeira AAR, Giordano RJ, Leite LCC, Pereira CAB, DeMarco R, Amaral MS, Verjovski-Almeida S.
Woellner-Santos D, et al.
NPJ Vaccines. 2024 Jan 4;9(1):5. doi: 10.1038/s41541-023-00803-x.
NPJ Vaccines. 2024.
PMID: 38177171
Free PMC article.
Developing a prophylactic vaccine against Schistosoma mansoni has been hindered by the parasite's biological complexity. In this study, we utilized the innovative phage-display immunoprecipitation followed by a sequencing approach (PhIP-Seq) to screen the immune response o …
Developing a prophylactic vaccine against Schistosoma mansoni has been hindered by the parasite's biological complexity. In this study, we u …