23187/CRUK_/Cancer Research UK/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2016	1
2017	2
2018	2
2019	7
2020	5
2021	3
2024	0

1

Tuning Local Hydration Enables a Deeper Understanding of Protein-Ligand Binding: The PP1-Src Kinase Case.

Spitaleri A, Zia SR, Di Micco P, Al-Lazikani B, Soler MA, Rocchia W. Spitaleri A, et al. J Phys Chem Lett. 2021 Jan 14;12(1):49-58. doi: 10.1021/acs.jpclett.0c03075. Epub 2020 Dec 10. J Phys Chem Lett. 2021. PMID: 33300337 Free PMC article.

2

canSAR: update to the cancer translational research and drug discovery knowledgebase.

Mitsopoulos C, Di Micco P, Fernandez EV, Dolciami D, Holt E, Mica IL, Coker EA, Tym JE, Campbell J, Che KH, Ozer B, Kannas C, Antolin AA, Workman P, Al-Lazikani B. Mitsopoulos C, et al. Nucleic Acids Res. 2021 Jan 8;49(D1):D1074-D1082. doi: 10.1093/nar/gkaa1059. Nucleic Acids Res. 2021. PMID: 33219674 Free PMC article.

3

Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.

Darby JF, Vidler LR, Simpson PJ, Al-Lazikani B, Matthews SJ, Sharp SY, Pearl LH, Hoelder S, Workman P. Darby JF, et al. Sci Rep. 2020 Sep 29;10(1):16000. doi: 10.1038/s41598-020-71969-w. Sci Rep. 2020. PMID: 32994435 Free PMC article.

4

Correction: Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.

Zhang C, Stockwell SR, Elbanna M, Ketteler R, Freeman J, Al-Lazikani B, Eccles S, De Haven Brandon A, Raynaud F, Hayes A, Clarke PA, Workman P, Mittnacht S. Zhang C, et al. Oncogene. 2020 Apr;39(16):3411-3412. doi: 10.1038/s41388-020-1221-8. Oncogene. 2020. PMID: 32094403 Free PMC article.

5

The kinase polypharmacology landscape of clinical PARP inhibitors.

Antolin AA, Ameratunga M, Banerji U, Clarke PA, Workman P, Al-Lazikani B. Antolin AA, et al. Sci Rep. 2020 Feb 17;10(1):2585. doi: 10.1038/s41598-020-59074-4. Sci Rep. 2020. PMID: 32066817 Free PMC article.

6

Public resources for chemical probes: the journey so far and the road ahead.

Antolin AA, Workman P, Al-Lazikani B. Antolin AA, et al. Future Med Chem. 2021 Apr;13(8):731-747. doi: 10.4155/fmc-2019-0231. Epub 2019 Nov 28. Future Med Chem. 2021. PMID: 31778323 Free article. Review.

7

PDBe-KB: a community-driven resource for structural and functional annotations.

PDBe-KB consortium. PDBe-KB consortium. Nucleic Acids Res. 2020 Jan 8;48(D1):D344-D353. doi: 10.1093/nar/gkz853. Nucleic Acids Res. 2020. PMID: 31584092 Free PMC article.

8

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations.

George SL, Izquierdo E, Campbell J, Koutroumanidou E, Proszek P, Jamal S, Hughes D, Yuan L, Marshall LV, Carceller F, Chisholm JC, Vaidya S, Mandeville H, Angelini P, Wasti A, Bexelius T, Thway K, Gatz SA, Clarke M, Al-Lazikani B, Barone G, Anderson J, Tweddle DA, Gonzalez D, Walker BA, Barton J, Depani S, Eze J, Ahmed SW, Moreno L, Pearson A, Shipley J, Jones C, Hargrave D, Jacques TS, Hubank M, Chesler L. George SL, et al. Eur J Cancer. 2019 Nov;121:224-235. doi: 10.1016/j.ejca.2019.07.027. Epub 2019 Sep 19. Eur J Cancer. 2019. PMID: 31543384 Free PMC article.

9

Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.

Zhang C, Stockwell SR, Elbanna M, Ketteler R, Freeman J, Al-Lazikani B, Eccles S, De Haven Brandon A, Raynaud F, Hayes A, Clarke PA, Workman P, Mittnacht S. Zhang C, et al. Oncogene. 2019 Jul;38(30):5905-5920. doi: 10.1038/s41388-019-0850-2. Epub 2019 Jul 12. Oncogene. 2019. PMID: 31296956 Free PMC article.

10

Transforming cancer drug discovery with Big Data and AI.

Workman P, Antolin AA, Al-Lazikani B. Workman P, et al. Expert Opin Drug Discov. 2019 Nov;14(11):1089-1095. doi: 10.1080/17460441.2019.1637414. Epub 2019 Jul 8. Expert Opin Drug Discov. 2019. PMID: 31284790 No abstract available.

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