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Year Number of Results
2017 2
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2020 6
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2022 5
2023 1
2024 0

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Page 1
Dual inhibition of HSF1 and DYRK2 impedes cancer progression.
Tandon V, Moreno R, Allmeroth K, Quinn J, Wiley SE, Nicely LG, Denzel MS, Edwards J, de la Vega L, Banerjee S. Tandon V, et al. Biosci Rep. 2023 Jan 31;43(1):BSR20222102. doi: 10.1042/BSR20222102. Biosci Rep. 2023. PMID: 36622366 Free PMC article.
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism.
Chen F, Elgaher WAM, Winterhoff M, Büssow K, Waqas FH, Graner E, Pires-Afonso Y, Casares Perez L, de la Vega L, Sahini N, Czichon L, Zobl W, Zillinger T, Shehata M, Pleschka S, Bähre H, Falk C, Michelucci A, Schuchardt S, Blankenfeldt W, Hirsch AKH, Pessler F. Chen F, et al. Nat Metab. 2022 May;4(5):534-546. doi: 10.1038/s42255-022-00577-x. Epub 2022 Jun 2. Nat Metab. 2022. PMID: 35655026 Free PMC article.
The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity.
Casares L, Moreno R, Ali KX, Higgins M, Dayalan Naidu S, Neill G, Cassin L, Kiib AE, Svenningsen EB, Minassi A, Honda T, Poulsen TB, Wiel C, Sayin VI, Dinkova-Kostova AT, Olagnier D, de la Vega L. Casares L, et al. Redox Biol. 2022 May;51:102291. doi: 10.1016/j.redox.2022.102291. Epub 2022 Mar 17. Redox Biol. 2022. PMID: 35313207 Free PMC article.
A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival.
Lara-Chica M, Correa-Sáez A, Jiménez-Izquierdo R, Garrido-Rodríguez M, Ponce FJ, Moreno R, Morrison K, Di Vona C, Arató K, Jiménez-Jiménez C, Morrugares R, Schmitz ML, de la Luna S, de la Vega L, Calzado MA. Lara-Chica M, et al. Cell Death Differ. 2022 Jan;29(1):105-117. doi: 10.1038/s41418-021-00845-5. Epub 2021 Aug 6. Cell Death Differ. 2022. PMID: 34363019 Free PMC article.
Emerging roles of DYRK2 in cancer.
Tandon V, de la Vega L, Banerjee S. Tandon V, et al. J Biol Chem. 2021 Jan-Jun;296:100233. doi: 10.1074/jbc.REV120.015217. Epub 2021 Jan 7. J Biol Chem. 2021. PMID: 33376136 Free PMC article. Review.
Downregulation of Keap1 Confers Features of a Fasted Metabolic State.
Knatko EV, Tatham MH, Zhang Y, Castro C, Higgins M, Dayalan Naidu S, Leonardi C, de la Vega L, Honda T, Griffin JL, Hay RT, Dinkova-Kostova AT. Knatko EV, et al. iScience. 2020 Oct 6;23(10):101638. doi: 10.1016/j.isci.2020.101638. eCollection 2020 Oct 23. iScience. 2020. PMID: 33103077 Free PMC article.
18 results