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Bexarotene drives the self-renewing proliferation of adult neural stem cells, promotes neuron-glial fate shift, and regulates late neuronal differentiation.
J Neurochem. 2023 Nov 20. doi: 10.1111/jnc.15998. Online ahead of print.
J Neurochem. 2023.
PMID: 37984072
Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE).
Peixoto DO, Bittencourt RR, Gasparotto J, Kessler FGC, Brum PO, Somensi N, Girardi CS, Dos Santos da Silva L, Outeiro TF, Moreira JCF, Gelain DP.
Peixoto DO, et al.
J Neurochem. 2023 Sep 3. doi: 10.1111/jnc.15956. Online ahead of print.
J Neurochem. 2023.
PMID: 37661637
Considering the role of this receptor in the initiation and establishment of neuroinflammation, and the limited understanding of the function of RAGE in the maintenance of this condition, this study describes the effects of RAGE inhibition in the brain, through an intranas …
Considering the role of this receptor in the initiation and establishment of neuroinflammation, and the limited understanding of the functio …
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Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease.
Gasparotto J, Somensi N, Girardi CS, Bittencourt RR, de Oliveira LM, Hoefel LP, Scheibel IM, Peixoto DO, Moreira JCF, Outeiro TF, Gelain DP.
Gasparotto J, et al.
J Neurochem. 2023 Jun 28. doi: 10.1111/jnc.15890. Online ahead of print.
J Neurochem. 2023.
PMID: 37381043
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