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Year Number of Results
2020 3
2021 6
2022 2
2023 2
2024 0

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11 results

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Page 1
Gene silencing dynamics are modulated by transiently active regulatory elements.
Vermunt MW, Luan J, Zhang Z, Thrasher AJ, Huang A, Saari MS, Khandros E, Beagrie RA, Zhang S, Vemulamada P, Brilleman M, Lee K, Yano JA, Giardine BM, Keller CA, Hardison RC, Blobel GA. Vermunt MW, et al. Mol Cell. 2023 Mar 2;83(5):715-730.e6. doi: 10.1016/j.molcel.2023.02.006. Mol Cell. 2023. PMID: 36868189 Free PMC article.
Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks.
Jung MM, Shen S, Botten GA, Olender T, Katsumura KR, Johnson KD, Soukup AA, Liu P, Zhang Q, Jensvold ZD, Lewis PW, Beagrie RA, Low JK, Yang L, Mackay JP, Godley LA, Brand M, Xu J, Keles S, Bresnick EH. Jung MM, et al. J Clin Invest. 2023 Apr 3;133(7):e162685. doi: 10.1172/JCI162685. J Clin Invest. 2023. PMID: 36809258 Free PMC article.
Scalable in vitro production of defined mouse erythroblasts.
Francis HS, Harold CL, Beagrie RA, King AJ, Gosden ME, Blayney JW, Jeziorska DM, Babbs C, Higgs DR, Kassouf MT. Francis HS, et al. PLoS One. 2022 Jan 7;17(1):e0261950. doi: 10.1371/journal.pone.0261950. eCollection 2022. PLoS One. 2022. PMID: 34995303 Free PMC article.
Reactivation of a developmentally silenced embryonic globin gene.
King AJ, Songdej D, Downes DJ, Beagrie RA, Liu S, Buckley M, Hua P, Suciu MC, Marieke Oudelaar A, Hanssen LLP, Jeziorska D, Roberts N, Carpenter SJ, Francis H, Telenius J, Olijnik AA, Sharpe JA, Sloane-Stanley J, Eglinton J, Kassouf MT, Orkin SH, Pennacchio LA, Davies JOJ, Hughes JR, Higgs DR, Babbs C. King AJ, et al. Nat Commun. 2021 Jul 21;12(1):4439. doi: 10.1038/s41467-021-24402-3. Nat Commun. 2021. PMID: 34290235 Free PMC article.
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale.
Downes DJ, Beagrie RA, Gosden ME, Telenius J, Carpenter SJ, Nussbaum L, De Ornellas S, Sergeant M, Eijsbouts CQ, Schwessinger R, Kerry J, Roberts N, Shivalingam A, El-Sagheer A, Oudelaar AM, Brown T, Buckle VJ, Davies JOJ, Hughes JR. Downes DJ, et al. Nat Commun. 2021 Jan 22;12(1):531. doi: 10.1038/s41467-020-20809-6. Nat Commun. 2021. PMID: 33483495 Free PMC article.
Recapitulation of erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities.
Scott C, Downes DJ, Brown JM, Beagrie R, Olijnik AA, Gosden M, Schwessinger R, Fisher CA, Rose A, Ferguson DJP, Johnson E, Hill QA, Okoli S, Renella R, Ryan K, Brand M, Hughes J, Roy NBA, Higgs DR, Babbs C, Buckle VJ. Scott C, et al. Haematologica. 2021 Nov 1;106(11):2960-2970. doi: 10.3324/haematol.2020.260158. Haematologica. 2021. PMID: 33121234 Free PMC article.
11 results