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Year Number of Results
2018 4
2019 7
2020 4
2021 4
2022 10
2023 1
2024 0

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27 results

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Page 1
Population Pharmacokinetic Analysis of Rifampicin in Plasma, Cerebrospinal Fluid, and Brain Extracellular Fluid in South African Children with Tuberculous Meningitis.
Abdelgawad N, Tshavhungwe MP, Rohlwink U, McIlleron H, Abdelwahab MT, Wiesner L, Castel S, Steele C, Enslin JN, Thango NS, Denti P, Figaji A. Abdelgawad N, et al. Antimicrob Agents Chemother. 2023 Mar 16;67(3):e0147422. doi: 10.1128/aac.01474-22. Epub 2023 Feb 23. Antimicrob Agents Chemother. 2023. PMID: 36815838 Free PMC article.
Pharmacokinetics of standard versus high-dose isoniazid for treatment of multidrug-resistant tuberculosis.
Gausi K, Chirehwa M, Ignatius EH, Court R, Sun X, Moran L, Hafner R, Wiesner L, Rosenkranz SL, de Jager V, de Vries N, Harding J, Gumbo T, Swindells S, Diacon A, Dooley KE, McIlleron H, Denti P. Gausi K, et al. J Antimicrob Chemother. 2022 Aug 25;77(9):2489-2499. doi: 10.1093/jac/dkac188. J Antimicrob Chemother. 2022. PMID: 35678468 Free PMC article.
The Effect of Rifampicin on Darunavir, Ritonavir, and Dolutegravir Exposure within Peripheral Blood Mononuclear Cells: a Dose Escalation Study.
De Nicolò A, Calcagno A, Motta I, De Vivo E, D'Avolio A, Di Perri G, Wiesner L, Ebrahim IE, Maartens G, Orrell C, McIlleron H. De Nicolò A, et al. Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0013622. doi: 10.1128/aac.00136-22. Epub 2022 May 18. Antimicrob Agents Chemother. 2022. PMID: 35583344 Free PMC article. Clinical Trial.
Pharmacokinetics and Dose Optimization Strategies of Para-Aminosalicylic Acid in Children with Rifampicin-Resistant Tuberculosis.
van der Laan LE, Garcia-Prats AJ, Schaaf HS, Chirehwa M, Winckler JL, Mao J, Draper HR, Wiesner L, Norman J, McIlleron H, Donald PR, Hesseling AC, Denti P. van der Laan LE, et al. Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0226421. doi: 10.1128/aac.02264-21. Epub 2022 May 4. Antimicrob Agents Chemother. 2022. PMID: 35506699 Free PMC article.
Population pharmacokinetics of ethambutol in African children: a pooled analysis.
Tikiso T, McIlleron H, Abdelwahab MT, Bekker A, Hesseling A, Chabala C, Davies G, Zar HJ, Rabie H, Andrieux-Meyer I, Lee J, Wiesner L, Cotton MF, Denti P. Tikiso T, et al. J Antimicrob Chemother. 2022 Jun 29;77(7):1949-1959. doi: 10.1093/jac/dkac127. J Antimicrob Chemother. 2022. PMID: 35466379 Free PMC article.
Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children.
Turkova A, Wills GH, Wobudeya E, Chabala C, Palmer M, Kinikar A, Hissar S, Choo L, Musoke P, Mulenga V, Mave V, Joseph B, LeBeau K, Thomason MJ, Mboizi RB, Kapasa M, van der Zalm MM, Raichur P, Bhavani PK, McIlleron H, Demers AM, Aarnoutse R, Love-Koh J, Seddon JA, Welch SB, Graham SM, Hesseling AC, Gibb DM, Crook AM; SHINE Trial Team. Turkova A, et al. N Engl J Med. 2022 Mar 10;386(10):911-922. doi: 10.1056/NEJMoa2104535. N Engl J Med. 2022. PMID: 35263517 Free PMC article. Clinical Trial.
Optimizing Dosing and Fixed-Dose Combinations of Rifampicin, Isoniazid, and Pyrazinamide in Pediatric Patients With Tuberculosis: A Prospective Population Pharmacokinetic Study.
Denti P, Wasmann RE, van Rie A, Winckler J, Bekker A, Rabie H, Hesseling AC, van der Laan LE, Gonzalez-Martinez C, Zar HJ, Davies G, Wiesner L, Svensson EM, McIlleron HM. Denti P, et al. Clin Infect Dis. 2022 Aug 24;75(1):141-151. doi: 10.1093/cid/ciab908. Clin Infect Dis. 2022. PMID: 34665866 Free PMC article.
Pharmacokinetics of First-Line Drugs in Children With Tuberculosis, Using World Health Organization-Recommended Weight Band Doses and Formulations.
Chabala C, Turkova A, Hesseling AC, Zimba KM, van der Zalm M, Kapasa M, Palmer M, Chirehwa M, Wiesner L, Wobudeya E, Kinikar A, Mave V, Hissar S, Choo L, LeBeau K, Mulenga V, Aarnoutse R, Gibb D, McIlleron H. Chabala C, et al. Clin Infect Dis. 2022 May 30;74(10):1767-1775. doi: 10.1093/cid/ciab725. Clin Infect Dis. 2022. PMID: 34420049 Free PMC article.
Relationship between Plasma and Intracellular Concentrations of Bedaquiline and Its M2 Metabolite in South African Patients with Rifampin-Resistant Tuberculosis.
Ngwalero P, Brust JCM, van Beek SW, Wasserman S, Maartens G, Meintjes G, Joubert A, Norman J, Castel S, Gandhi NR, Denti P, McIlleron H, Svensson EM, Wiesner L. Ngwalero P, et al. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0239920. doi: 10.1128/AAC.02399-20. Epub 2021 Aug 9. Antimicrob Agents Chemother. 2021. PMID: 34370588 Free PMC article.
27 results