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Page 1
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Ryan TAJ, Hooftman A, Rehill AM, Johansen MD, Brien ECO, Toller-Kawahisa JE, Wilk MM, Day EA, Weiss HJ, Sarvari P, Vozza EG, Schramm F, Peace CG, Zotta A, Miemczyk S, Nalkurthi C, Hansbro NG, McManus G, O'Doherty L, Gargan S, Long A, Dunne J, Cheallaigh CN, Conlon N, Carty M, Fallon PG, Mills KHG, Creagh EM, Donnell JSO, Hertzog PJ, Hansbro PM, McLoughlin RM, Wygrecka M, Preston RJS, Zasłona Z, O'Neill LAJ. Ryan TAJ, et al. Nat Commun. 2023 Jun 14;14(1):3513. doi: 10.1038/s41467-023-39174-1. Nat Commun. 2023. PMID: 37316487 Free PMC article.
PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection.
Baran M, Feriotti C, McGinley A, Carlile SR, Jiang Z, Calderon-Gonzalez R, Dumigan A, Sá-Pessoa J, Sutton CE, Kearney J, McLoughlin RM, Mills KHG, Fitzgerald KA, Bengeochea JA, Bowie AG. Baran M, et al. Cell Rep. 2023 Apr 25;42(4):112341. doi: 10.1016/j.celrep.2023.112341. Epub 2023 Apr 4. Cell Rep. 2023. PMID: 37018072 Free article.
Targeted control of pneumolysin production by a mobile genetic element in Streptococcus pneumoniae.
Stevens EJ, Morse DJ, Bonini D, Duggan S, Brignoli T, Recker M, Lees JA, Croucher NJ, Bentley S, Wilson DJ, Earle SG, Dixon R, Nobbs A, Jenkinson H, van Opijnen T, Thibault D, Wilkinson OJ, Dillingham MS, Carlile S, McLoughlin RM, Massey RC. Stevens EJ, et al. Microb Genom. 2022 Apr;8(4):000784. doi: 10.1099/mgen.0.000784. Microb Genom. 2022. PMID: 35416147 Free PMC article.