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Protein Tyrosine Phosphatase PRL-3: A Key Player in Cancer Signaling.
Liu H, Li X, Shi Y, Ye Z, Cheng X. Liu H, et al. Biomolecules. 2024 Mar 12;14(3):342. doi: 10.3390/biom14030342. Biomolecules. 2024. PMID: 38540761 Free PMC article. Review.
PRL-3's involvement in proliferation, migration, invasion, metastasis, angiogenesis, and drug resistance is discussed. Regulatory mechanisms encompass transcriptional control, alternative splicing, and post-translational modifications. ...
PRL-3's involvement in proliferation, migration, invasion, metastasis, angiogenesis, and drug resistance is discussed. Regulatory mechanisms …
Blocking Ubiquitin-Specific Protease 7 Induces Ferroptosis in Gastric Cancer via Targeting Stearoyl-CoA Desaturase.
Guan X, Wang Y, Yu W, Wei Y, Lu Y, Dai E, Dong X, Zhao B, Hu C, Yuan L, Luan X, Miao K, Chen B, Cheng XD, Zhang W, Qin JJ. Guan X, et al. Adv Sci (Weinh). 2024 Mar 9:e2307899. doi: 10.1002/advs.202307899. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38460164
DHPO demonstrates significant anti-tumor activity in vitro, inhibiting cell viability and clonogenic ability, and preventing tumor migration and invasion. In vivo studies using orthotopic gastric tumor mouse models validate DHPO's efficacy in suppressing tumor growth and m …
DHPO demonstrates significant anti-tumor activity in vitro, inhibiting cell viability and clonogenic ability, and preventing tumor mi …