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(+)-Lipoic Acid Reduces Lipotoxicity and Regulates Mitochondrial Homeostasis and Energy Balance in an In Vitro Model of Liver Steatosis.
Longhitano L, Distefano A, Amorini AM, Orlando L, Giallongo S, Tibullo D, Lazzarino G, Nicolosi A, Alanazi AM, Saoca C, Macaione V, Aguennouz M, Salomone F, Tropea E, Barbagallo IA, Volti GL, Lazzarino G. Longhitano L, et al. Int J Mol Sci. 2023 Sep 23;24(19):14491. doi: 10.3390/ijms241914491. Int J Mol Sci. 2023. PMID: 37833939 Free PMC article.
HepG2 cells were treated with palmitic acid and oleic acid (1:2) to induce steatosis, without and with 1 and 5 M lipoic acid. ...
HepG2 cells were treated with palmitic acid and oleic acid (1:2) to induce steatosis, without and with 1 and 5 M lipoic acid. ...
Lactate modulates microglia polarization via IGFBP6 expression and remodels tumor microenvironment in glioblastoma.
Longhitano L, Vicario N, Forte S, Giallongo C, Broggi G, Caltabiano R, Barbagallo GMV, Altieri R, Raciti G, Di Rosa M, Caruso M, Parenti R, Liso A, Busi F, Lolicato M, Mione MC, Li Volti G, Tibullo D. Longhitano L, et al. Cancer Immunol Immunother. 2023 Jan;72(1):1-20. doi: 10.1007/s00262-022-03215-3. Epub 2022 Jun 3. Cancer Immunol Immunother. 2023. PMID: 35654889 Free PMC article.