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Chemical Structure and Anticoagulant Property of a Novel Sulfated Polysaccharide from the Green Alga Cladophora oligoclada.
He M, Yang Y, Shao Z, Zhang J, Feng C, Wang L, Mao W. He M, et al. Mar Drugs. 2021 Sep 29;19(10):554. doi: 10.3390/md19100554. Mar Drugs. 2021. PMID: 34677453 Free PMC article.
The sulfated polysaccharide exhibited potent anticoagulant activity in vitro and in vivo as evaluated by activated partial thromboplastin time (APTT), thrombin time, and the fibrinogen level. For the APTT, the signal for clotting time was more than 200 s at 100 mug/mL in v …
The sulfated polysaccharide exhibited potent anticoagulant activity in vitro and in vivo as evaluated by activated partial thromboplastin ti …