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A possible solution to model nonlinearity in elimination and distributional clearances with α2 -adrenergic receptor agonists: Example of the intravenous detomidine and methadone combination in sedated horses.
J Vet Pharmacol Ther. 2019 Nov;42(6):738-744. doi: 10.1111/jvp.12815. Epub 2019 Oct 4.
J Vet Pharmacol Ther. 2019.
PMID: 31584710
Free article.
Characterisation of the in vivo interactions between detomidine and methadone in horses: Pharmacokinetic and pharmacodynamic modelling.
Gozalo-Marcilla M, Luna SPL, Moreira da Silva R, Crosignani N, Lopes NP, Taylor PM, Pelligand L.
Gozalo-Marcilla M, et al.
Equine Vet J. 2019 Jul;51(4):517-529. doi: 10.1111/evj.13031. Epub 2018 Nov 17.
Equine Vet J. 2019.
PMID: 30298682
Free article.
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