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Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.
Barrott JJ, Hughes PF, Osada T, Yang XY, Hartman ZC, Loiselle DR, Spector NL, Neckers L, Rajaram N, Hu F, Ramanujam N, Vaidyanathan G, Zalutsky MR, Lyerly HK, Haystead TA. Barrott JJ, et al. Chem Biol. 2013 Sep 19;20(9):1187-97. doi: 10.1016/j.chembiol.2013.08.004. Epub 2013 Sep 12. Chem Biol. 2013. PMID: 24035283 Free PMC article.
Hsp90, an unlikely ally in the war on cancer.
Barrott JJ, Haystead TA. Barrott JJ, et al. FEBS J. 2013 Mar;280(6):1381-96. doi: 10.1111/febs.12147. Epub 2013 Feb 24. FEBS J. 2013. PMID: 23356585 Free PMC article. Review.