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2010 1
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Page 1
Pim-1 kinase protects mitochondrial integrity in cardiomyocytes.
Borillo GA, Mason M, Quijada P, Völkers M, Cottage C, McGregor M, Din S, Fischer K, Gude N, Avitabile D, Barlow S, Alvarez R, Truffa S, Whittaker R, Glassy MS, Gustafsson AB, Miyamoto S, Glembotski CC, Gottlieb RA, Brown JH, Sussman MA. Borillo GA, et al. Circ Res. 2010 Apr 16;106(7):1265-74. doi: 10.1161/CIRCRESAHA.109.212035. Epub 2010 Mar 4. Circ Res. 2010. PMID: 20203306 Free PMC article.
Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload.
Muraski JA, Fischer KM, Wu W, Cottage CT, Quijada P, Mason M, Din S, Gude N, Alvarez R Jr, Rota M, Kajstura J, Wang Z, Schaefer E, Chen X, MacDonnel S, Magnuson N, Houser SR, Anversa P, Sussman MA. Muraski JA, et al. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13889-94. doi: 10.1073/pnas.0709135105. Epub 2008 Sep 10. Proc Natl Acad Sci U S A. 2008. PMID: 18784362 Free PMC article.
Activation of Notch-mediated protective signaling in the myocardium.
Gude NA, Emmanuel G, Wu W, Cottage CT, Fischer K, Quijada P, Muraski JA, Alvarez R, Rubio M, Schaefer E, Sussman MA. Gude NA, et al. Circ Res. 2008 May 9;102(9):1025-35. doi: 10.1161/CIRCRESAHA.107.164749. Epub 2008 Mar 27. Circ Res. 2008. PMID: 18369158 Free PMC article.
Pim-1 regulates cardiomyocyte survival downstream of Akt.
Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, Glembotski CC, Leri A, Kajstura J, Magnuson N, Berns A, Beretta RM, Houser SR, Schaefer EM, Anversa P, Sussman MA. Muraski JA, et al. Nat Med. 2007 Dec;13(12):1467-75. doi: 10.1038/nm1671. Epub 2007 Nov 25. Nat Med. 2007. PMID: 18037896