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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2015 1
2016 2
2017 4
2018 241
2019 267
2020 264
2021 489
2022 367
2023 173
2024 237

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1,819 results

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Page 1
Scalable telomere-to-telomere assembly for diploid and polyploid genomes with double graph.
Cheng H, Asri M, Lucas J, Koren S, Li H. Cheng H, et al. Nat Methods. 2024 May 10. doi: 10.1038/s41592-024-02269-8. Online ahead of print. Nat Methods. 2024. PMID: 38730258
Here we present hifiasm (UL), an efficient de novo assembly algorithm combining multiple sequencing technologies to scale up population-wide near telomere-to-telomere assemblies. Applied to 22 human and two plant genomes, our algorithm produces better diploid assemblies at …
Here we present hifiasm (UL), an efficient de novo assembly algorithm combining multiple sequencing technologies to scale up population-wide …
Prime editing-mediated correction of the leptin receptor in muscle cells of db/db mice.
Lee KE, Xu Y, Geng B, Kim J, Kellon N, He Z, Zhang Z, Li D, Gouchoe DA, Zhu H. Lee KE, et al. Biotechnol J. 2024 May;19(5):e2300676. doi: 10.1002/biot.202300676. Biotechnol J. 2024. PMID: 38730523
A specific type of genomic editing, prime editing, has the potential advantage to edit the human genome without requiring double-strand breaks or donor DNA templates for editing. ...
A specific type of genomic editing, prime editing, has the potential advantage to edit the human genome without requiring double-stra …
hiPSC-CM Electrophysiology: Impact of Temporal Changes and Study Parameters on Experimental Reproducibility.
Guerrelli D, Pressman J, Salameh S, Posnack NG. Guerrelli D, et al. Am J Physiol Heart Circ Physiol. 2024 May 10. doi: 10.1152/ajpheart.00631.2023. Online ahead of print. Am J Physiol Heart Circ Physiol. 2024. PMID: 38727253
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are frequently used for preclinical cardiotoxicity testing and remain an important tool for confirming model-based predictions of drug effects in accordance with Comprehensive in Vitro Proarrhythmia Ass …
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are frequently used for preclinical cardiotoxicity testing and …
Diffusion-tensor-imaging 1-year-old and 2-year-old infant brain atlases with comprehensive gray and white matter labels.
Song L, Peng Y, Ouyang M, Peng Q, Feng L, Sotardi S, Yu Q, Kang H, Sindabizera KL, Liu S, Huang H. Song L, et al. Hum Brain Mapp. 2024 May;45(7):e26695. doi: 10.1002/hbm.26695. Hum Brain Mapp. 2024. PMID: 38727010
Human infancy is marked by fastest postnatal brain structural changes. ...
Human infancy is marked by fastest postnatal brain structural changes. ...
Exercise MR of Skeletal Muscles, the Heart, and the Brain.
Hooijmans MT, Jeneson JAL, Jørstad HT, Bakermans AJ. Hooijmans MT, et al. J Magn Reson Imaging. 2024 May 10. doi: 10.1002/jmri.29445. Online ahead of print. J Magn Reson Imaging. 2024. PMID: 38726984 Review.
Magnetic resonance (MR) imaging (MRI) is routinely used to evaluate organ morphology and pathology in the human body at rest or in combination with pharmacological stress as an exercise surrogate. ...Although not yet integrated in most clinical workflows, and while some ap …
Magnetic resonance (MR) imaging (MRI) is routinely used to evaluate organ morphology and pathology in the human body at rest or in co …
Direct transposition of native DNA for sensitive multimodal single-molecule sequencing.
Nanda AS, Wu K, Irkliyenko I, Woo B, Ostrowski MS, Clugston AS, Sayles LC, Xu L, Satpathy AT, Nguyen HG, Alejandro Sweet-Cordero E, Goodarzi H, Kasinathan S, Ramani V. Nanda AS, et al. Nat Genet. 2024 May 9. doi: 10.1038/s41588-024-01748-0. Online ahead of print. Nat Genet. 2024. PMID: 38724748
We developed two methods that implement tagmentation and use 90-99% less input than current protocols: (1) single-molecule real-time sequencing by tagmentation (SMRT-Tag), which allows detection of genetic variation and CpG methylation; and (2) single-molecule adenine-methylated …
We developed two methods that implement tagmentation and use 90-99% less input than current protocols: (1) single-molecule real-time sequenc …
Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders.
Luo J, Li L, Niu M, Kong D, Jiang Y, Poudel S, Shieh AW, Cheng L, Giase G, Grennan K, White KP, Chen C, Wang SH, Pinto D, Wang Y, Liu C, Peng J, Wang X. Luo J, et al. Mol Psychiatry. 2024 May 9. doi: 10.1038/s41380-024-02576-8. Online ahead of print. Mol Psychiatry. 2024. PMID: 38724566
Genome-wide association studies have identified hundreds of genomic susceptibility loci with susceptibility to psychiatric disorders; however, the contribution of these loci to the underlying psychopathology and etiology remains elusive. Here we generated deep human brain …
Genome-wide association studies have identified hundreds of genomic susceptibility loci with susceptibility to psychiatric disorders; howeve …
1,819 results