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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2015 | 2 |
2016 | 3 |
2020 | 1 |
2021 | 1 |
2024 | 0 |
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6 results
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Page 1
Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells.
Int J Mol Sci. 2021 Mar 26;22(7):3410. doi: 10.3390/ijms22073410.
Int J Mol Sci. 2021.
PMID: 33810274
Free PMC article.
Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm.
Bauer MR, Krämer A, Settanni G, Jones RN, Ni X, Khan Tareque R, Fersht AR, Spencer J, Joerger AC.
Bauer MR, et al.
ACS Chem Biol. 2020 Mar 20;15(3):657-668. doi: 10.1021/acschembio.9b00748. Epub 2020 Feb 21.
ACS Chem Biol. 2020.
PMID: 31990523
Free PMC article.
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Elaboration of tetra-orthogonally-substituted aromatic scaffolds towards novel EGFR-kinase inhibitors.
Close AJ, Jones RN, Ocasio CA, Kemmitt P, Roe SM, Spencer J.
Close AJ, et al.
Org Biomol Chem. 2016 Sep 21;14(35):8246-52. doi: 10.1039/c6ob01394e. Epub 2016 Jul 25.
Org Biomol Chem. 2016.
PMID: 27453149
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Harnessing Fluorine-Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs.
Bauer MR, Jones RN, Baud MG, Wilcken R, Boeckler FM, Fersht AR, Joerger AC, Spencer J.
Bauer MR, et al.
ACS Chem Biol. 2016 Aug 19;11(8):2265-74. doi: 10.1021/acschembio.6b00315. Epub 2016 Jun 21.
ACS Chem Biol. 2016.
PMID: 27267810
Free PMC article.
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A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain.
Cox OB, Krojer T, Collins P, Monteiro O, Talon R, Bradley A, Fedorov O, Amin J, Marsden BD, Spencer J, von Delft F, Brennan PE.
Cox OB, et al.
Chem Sci. 2016 Mar 1;7(3):2322-2330. doi: 10.1039/c5sc03115j. Epub 2015 Dec 22.
Chem Sci. 2016.
PMID: 29910922
Free PMC article.
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Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant p53.
Joerger AC, Bauer MR, Wilcken R, Baud MGJ, Harbrecht H, Exner TE, Boeckler FM, Spencer J, Fersht AR.
Joerger AC, et al.
Structure. 2015 Dec 1;23(12):2246-2255. doi: 10.1016/j.str.2015.10.016.
Structure. 2015.
PMID: 26636255
Free PMC article.
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