123306 /CIHR/Canada[Grants and Funding] - Search Results

Year	Number of Results
2017	3
2018	1
2019	3
2020	4
2021	2
2022	1
2024	0

1

Spt20, a Structural Subunit of the SAGA Complex, Regulates Aspergillus fumigatus Biofilm Formation, Asexual Development, and Virulence.

Chen Y, Stewart JIP, Liu S, Sheppard DC, Lu L, Zhang S. Chen Y, et al. Appl Environ Microbiol. 2022 Jan 11;88(1):e0153521. doi: 10.1128/AEM.01535-21. Epub 2021 Oct 20. Appl Environ Microbiol. 2022. PMID: 34669434 Free PMC article.

2

The IL-1 Receptor Is Required to Maintain Neutrophil Viability and Function During Aspergillus fumigatus Airway Infection.

Ralph BA, Lehoux M, Ostapska H, Snarr BD, Caffrey-Carr AK, Fraser R, Saleh M, Obar JJ, Qureshi ST, Sheppard DC. Ralph BA, et al. Front Immunol. 2021 Jul 12;12:675294. doi: 10.3389/fimmu.2021.675294. eCollection 2021. Front Immunol. 2021. PMID: 34322116 Free PMC article.

3

The Transcription Factor SomA Synchronously Regulates Biofilm Formation and Cell Wall Homeostasis in Aspergillus fumigatus.

Chen Y, Le Mauff F, Wang Y, Lu R, Sheppard DC, Lu L, Zhang S. Chen Y, et al. mBio. 2020 Nov 10;11(6):e02329-20. doi: 10.1128/mBio.02329-20. mBio. 2020. PMID: 33173002 Free PMC article.

4

Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection.

Snarr BD, St-Pierre G, Ralph B, Lehoux M, Sato Y, Rancourt A, Takazono T, Baistrocchi SR, Corsini R, Cheng MP, Sugrue M, Baden LR, Izumikawa K, Mukae H, Wingard JR, King IL, Divangahi M, Satoh MS, Yipp BG, Sato S, Sheppard DC. Snarr BD, et al. PLoS Pathog. 2020 Aug 4;16(8):e1008741. doi: 10.1371/journal.ppat.1008741. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32750085 Free PMC article.

5

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation.

Bamford NC, Le Mauff F, Van Loon JC, Ostapska H, Snarr BD, Zhang Y, Kitova EN, Klassen JS, Codée JDC, Sheppard DC, Howell PL. Bamford NC, et al. Nat Commun. 2020 May 15;11(1):2450. doi: 10.1038/s41467-020-16144-5. Nat Commun. 2020. PMID: 32415073 Free PMC article.

6

Galactosaminogalactan secreted from Aspergillus fumigatus and Aspergillus flavus induces platelet activation.

Deshmukh H, Rambach G, Sheppard DC, Lee M, Hagleitner M, Hermann M, Würzner R, Lass-Flörl C, Speth C. Deshmukh H, et al. Microbes Infect. 2020 Sep;22(8):331-339. doi: 10.1016/j.micinf.2019.12.004. Epub 2020 Jan 18. Microbes Infect. 2020. PMID: 31962135 Free article.

7

Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1,4-galactosaminidase that disrupts microbial biofilms.

Bamford NC, Le Mauff F, Subramanian AS, Yip P, Millán C, Zhang Y, Zacharias C, Forman A, Nitz M, Codée JDC, Usón I, Sheppard DC, Howell PL. Bamford NC, et al. J Biol Chem. 2019 Sep 13;294(37):13833-13849. doi: 10.1074/jbc.RA119.009910. Epub 2019 Aug 15. J Biol Chem. 2019. PMID: 31416836 Free PMC article.

8

Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases.

Le Mauff F, Bamford NC, Alnabelseya N, Zhang Y, Baker P, Robinson H, Codée JDC, Howell PL, Sheppard DC. Le Mauff F, et al. J Biol Chem. 2019 Jul 12;294(28):10760-10772. doi: 10.1074/jbc.RA119.008511. Epub 2019 Jun 5. J Biol Chem. 2019. PMID: 31167793 Free PMC article.

9

The mitochondrial thiamine pyrophosphate transporter TptA promotes adaptation to low iron conditions and virulence in fungal pathogen Aspergillus fumigatus.

Huang J, Ma Z, Zhong G, Sheppard DC, Lu L, Zhang S. Huang J, et al. Virulence. 2019 Dec;10(1):234-247. doi: 10.1080/21505594.2019.1596505. Virulence. 2019. PMID: 30880633 Free PMC article.

10

PtaB, a lim-domain binding protein in Aspergillus fumigatus regulates biofilm formation and conidiation through distinct pathways.

Zhang S, Chen Y, Ma Z, Chen Q, Ostapska H, Gravelat FN, Lu L, Sheppard DC. Zhang S, et al. Cell Microbiol. 2018 Jan;20(1). doi: 10.1111/cmi.12799. Epub 2017 Nov 17. Cell Microbiol. 2018. PMID: 29114981

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