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Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors.
Muliaditan T, Halim L, Whilding LM, Draper B, Achkova DY, Kausar F, Glover M, Bechman N, Arulappu A, Sanchez J, Flaherty KR, Obajdin J, Grigoriadis K, Antoine P, Larcombe-Young D, Hull CM, Buus R, Gordon P, Grigoriadis A, Davies DM, Schurich A, Maher J. Muliaditan T, et al. Cell Rep Med. 2021 Dec 21;2(12):100457. doi: 10.1016/j.xcrm.2021.100457. eCollection 2021 Dec 21. Cell Rep Med. 2021. PMID: 35028604 Free PMC article.
Stem/progenitor cells in normal physiology and disease of the pancreas.
Alvarez Fallas ME, Pedraza-Arevalo S, Cujba AM, Manea T, Lambert C, Morrugares R, Sancho R. Alvarez Fallas ME, et al. Mol Cell Endocrinol. 2021 Dec 1;538:111459. doi: 10.1016/j.mce.2021.111459. Epub 2021 Sep 20. Mol Cell Endocrinol. 2021. PMID: 34543699 Free PMC article. Review.