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Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models.
Liu PJ, Harris JM, Marchi E, D'Arienzo V, Michler T, Wing PAC, Magri A, Ortega-Prieto AM, van de Klundert M, Wettengel J, Durantel D, Dorner M, Klenerman P, Protzer U, Giotis ES, McKeating JA. Liu PJ, et al. Sci Rep. 2020 Aug 24;10(1):14101. doi: 10.1038/s41598-020-70865-7. Sci Rep. 2020. PMID: 32839523 Free PMC article.
The Stronger Downregulation of in vitro and in vivo Innate Antiviral Responses by a Very Virulent Strain of Infectious Bursal Disease Virus (IBDV), Compared to a Classical Strain, Is Mediated, in Part, by the VP4 Protein.
Dulwich KL, Asfor A, Gray A, Giotis ES, Skinner MA, Broadbent AJ. Dulwich KL, et al. Front Cell Infect Microbiol. 2020 Jun 9;10:315. doi: 10.3389/fcimb.2020.00315. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32582573 Free PMC article.
Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry.
Mazzon M, Ortega-Prieto AM, Imrie D, Luft C, Hess L, Czieso S, Grove J, Skelton JK, Farleigh L, Bugert JJ, Wright E, Temperton N, Angell R, Oxenford S, Jacobs M, Ketteler R, Dorner M, Marsh M. Mazzon M, et al. Viruses. 2019 Feb 20;11(2):176. doi: 10.3390/v11020176. Viruses. 2019. PMID: 30791609 Free PMC article.
In Vivo Model Systems for Hepatitis B Virus Research.
Ortega-Prieto AM, Cherry C, Gunn H, Dorner M. Ortega-Prieto AM, et al. ACS Infect Dis. 2019 May 10;5(5):688-702. doi: 10.1021/acsinfecdis.8b00223. Epub 2019 Jan 8. ACS Infect Dis. 2019. PMID: 30539633 Free PMC article. Review.