100298/Wellcome Trust/United Kingdom[Grants and Funding] - Search Results

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Subject: 100298/Wellcome Trust/United Kingdom[Grants and F - PubMed

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The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.

Martins T, Meng Y, Korona B, Suckling R, Johnson S, Handford PA, Lea SM, Bray SJ. Martins T, et al. EMBO Rep. 2021 Oct 5;22(10):e52729. doi: 10.15252/embr.202152729. Epub 2021 Aug 4. EMBO Rep. 2021. PMID: 34347930 Free PMC article.

The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems.

Johnson S, Kuhlen L, Deme JC, Abrusci P, Lea SM. Johnson S, et al. mBio. 2019 Jun 25;10(3):e00818-19. doi: 10.1128/mBio.00818-19. mBio. 2019. PMID: 31239376 Free PMC article.

Virulence Associated Gene 8 of Bordetella pertussis Enhances Contact System Activity by Inhibiting the Regulatory Function of Complement Regulator C1 Inhibitor.

Hovingh ES, de Maat S, Cloherty APM, Johnson S, Pinelli E, Maas C, Jongerius I. Hovingh ES, et al. Front Immunol. 2018 Jun 4;9:1172. doi: 10.3389/fimmu.2018.01172. eCollection 2018. Front Immunol. 2018. PMID: 29915576 Free PMC article.

Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands.

Taylor P, Takeuchi H, Sheppard D, Chillakuri C, Lea SM, Haltiwanger RS, Handford PA. Taylor P, et al. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7290-5. doi: 10.1073/pnas.1319683111. Epub 2014 May 6. Proc Natl Acad Sci U S A. 2014. PMID: 24803430 Free PMC article.

Structural biology of Tat protein transport.

Berks BC, Lea SM, Stansfeld PJ. Berks BC, et al. Curr Opin Struct Biol. 2014 Aug;27:32-7. doi: 10.1016/j.sbi.2014.03.003. Epub 2014 Apr 5. Curr Opin Struct Biol. 2014. PMID: 24709396 Free article. Review.

The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation.

Conduit PT, Feng Z, Richens JH, Baumbach J, Wainman A, Bakshi SD, Dobbelaere J, Johnson S, Lea SM, Raff JW. Conduit PT, et al. Dev Cell. 2014 Mar 31;28(6):659-69. doi: 10.1016/j.devcel.2014.02.013. Epub 2014 Mar 20. Dev Cell. 2014. PMID: 24656740 Free PMC article.

Structural analysis uncovers lipid-binding properties of Notch ligands.

Chillakuri CR, Sheppard D, Ilagan MX, Holt LR, Abbott F, Liang S, Kopan R, Handford PA, Lea SM. Chillakuri CR, et al. Cell Rep. 2013 Nov 27;5(4):861-7. doi: 10.1016/j.celrep.2013.10.029. Epub 2013 Nov 14. Cell Rep. 2013. PMID: 24239355 Free PMC article.

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