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High-level production of recombinant HBcAg virus-like particles in a mathematically modelled P. pastoris GS115 Mut+ bioreactor process under controlled residual methanol concentration.
Bioprocess Biosyst Eng. 2022 Sep;45(9):1447-1463. doi: 10.1007/s00449-022-02754-4. Epub 2022 Aug 8.
Bioprocess Biosyst Eng. 2022.
PMID: 35939139
Free PMC article.
Application of In-Situ and Soft-Sensors for Estimation of Recombinant P. pastoris GS115 Biomass Concentration: A Case Analysis of HBcAg (Mut+) and HBsAg (MutS) Production Processes under Varying Conditions.
Grigs O, Bolmanis E, Galvanauskas V.
Grigs O, et al.
Sensors (Basel). 2021 Feb 10;21(4):1268. doi: 10.3390/s21041268.
Sensors (Basel). 2021.
PMID: 33578904
Free PMC article.
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