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Page 1
Chromatin jets define the properties of cohesin-driven in vivo loop extrusion.
Guo Y, Al-Jibury E, Garcia-Millan R, Ntagiantas K, King JWD, Nash AJ, Galjart N, Lenhard B, Rueckert D, Fisher AG, Pruessner G, Merkenschlager M. Guo Y, et al. Mol Cell. 2022 Oct 20;82(20):3769-3780.e5. doi: 10.1016/j.molcel.2022.09.003. Epub 2022 Sep 30. Mol Cell. 2022. PMID: 36182691 Free article.
Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters.
Robles-Rebollo I, Cuartero S, Canellas-Socias A, Wells S, Karimi MM, Mereu E, Chivu AG, Heyn H, Whilding C, Dormann D, Marguerat S, Rioja I, Prinjha RK, Stumpf MPH, Fisher AG, Merkenschlager M. Robles-Rebollo I, et al. Nat Commun. 2022 Jul 27;13(1):4342. doi: 10.1038/s41467-022-31192-9. Nat Commun. 2022. PMID: 35896525 Free PMC article.
Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice.
Van de Pette M, Dimond A, Galvão AM, Millership SJ, To W, Prodani C, McNamara G, Bruno L, Sardini A, Webster Z, McGinty J, French PMW, Uren AG, Castillo-Fernandez J, Watkinson W, Ferguson-Smith AC, Merkenschlager M, John RM, Kelsey G, Fisher AG. Van de Pette M, et al. Nat Commun. 2022 May 5;13(1):2464. doi: 10.1038/s41467-022-30022-2. Nat Commun. 2022. PMID: 35513363 Free PMC article.
Cohesin-dependence of neuronal gene expression relates to chromatin loop length.
Calderon L, Weiss FD, Beagan JA, Oliveira MS, Georgieva R, Wang YF, Carroll TS, Dharmalingam G, Gong W, Tossell K, de Paola V, Whilding C, Ungless MA, Fisher AG, Phillips-Cremins JE, Merkenschlager M. Calderon L, et al. Elife. 2022 Apr 26;11:e76539. doi: 10.7554/eLife.76539. Elife. 2022. PMID: 35471149 Free PMC article.
The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus.
Karimi MM, Guo Y, Cui X, Pallikonda HA, Horková V, Wang YF, Gil SR, Rodriguez-Esteban G, Robles-Rebollo I, Bruno L, Georgieva R, Patel B, Elliott J, Dore MH, Dauphars D, Krangel MS, Lenhard B, Heyn H, Fisher AG, Štěpánek O, Merkenschlager M. Karimi MM, et al. Nat Commun. 2021 Jan 4;12(1):99. doi: 10.1038/s41467-020-20306-w. Nat Commun. 2021. PMID: 33397934 Free PMC article.
Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation.
Ferreirós-Vidal I, Carroll T, Zhang T, Lagani V, Ramirez RN, Ing-Simmons E, Gómez-Valadés AG, Cooper L, Liang Z, Papoutsoglou G, Dharmalingam G, Guo Y, Tarazona S, Fernandes SJ, Noori P, Silberberg G, Fisher AG, Tsamardinos I, Mortazavi A, Lenhard B, Conesa A, Tegner J, Merkenschlager M, Gomez-Cabrero D. Ferreirós-Vidal I, et al. PLoS Biol. 2019 Apr 12;17(4):e2006506. doi: 10.1371/journal.pbio.2006506. eCollection 2019 Apr. PLoS Biol. 2019. PMID: 30978178 Free PMC article.
A high-resolution map of transcriptional repression.
Liang Z, Brown KE, Carroll T, Taylor B, Vidal IF, Hendrich B, Rueda D, Fisher AG, Merkenschlager M. Liang Z, et al. Elife. 2017 Mar 20;6:e22767. doi: 10.7554/eLife.22767. Elife. 2017. PMID: 28318487 Free PMC article.