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The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces.
Scheidt T, Carozza JA, Kolbe CC, Aprile FA, Tkachenko O, Bellaiche MMJ, Meisl G, Peter QAE, Herling TW, Ness S, Castellana-Cruz M, Benesch JLP, Vendruscolo M, Dobson CM, Arosio P, Knowles TPJ. Scheidt T, et al. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2108790118. doi: 10.1073/pnas.2108790118. Proc Natl Acad Sci U S A. 2021. PMID: 34518228 Free PMC article.
Probing the unfolded protein response in long-lived naked mole-rats.
Du Z, Chakrabarti S, Kulaberoglu Y, Smith ESJ, Dobson CM, Itzhaki LS, Kumita JR. Du Z, et al. Biochem Biophys Res Commun. 2020 Sep 3;529(4):1151-1157. doi: 10.1016/j.bbrc.2020.06.118. Epub 2020 Aug 3. Biochem Biophys Res Commun. 2020. PMID: 32819579 Free PMC article.
Amyloid-like Fibrils from an α-Helical Transmembrane Protein.
Stroobants K, Kumita JR, Harris NJ, Chirgadze DY, Dobson CM, Booth PJ, Vendruscolo M. Stroobants K, et al. Biochemistry. 2017 Jun 27;56(25):3225-3233. doi: 10.1021/acs.biochem.7b00157. Epub 2017 Jun 12. Biochemistry. 2017. PMID: 28493669 Free PMC article.