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Cotrimoxazole reduces systemic inflammation in HIV infection by altering the gut microbiome and immune activation.
Bourke CD, Gough EK, Pimundu G, Shonhai A, Berejena C, Terry L, Baumard L, Choudhry N, Karmali Y, Bwakura-Dangarembizi M, Musiime V, Lutaakome J, Kekitiinwa A, Mutasa K, Szubert AJ, Spyer MJ, Deayton JR, Glass M, Geum HM, Pardieu C, Gibb DM, Klein N, Edens TJ, Walker AS, Manges AR, Prendergast AJ. Bourke CD, et al. Sci Transl Med. 2019 Apr 3;11(486):eaav0537. doi: 10.1126/scitranslmed.aav0537. Sci Transl Med. 2019. PMID: 30944164 Free PMC article. Clinical Trial.
A randomized trial of prolonged co-trimoxazole in HIV-infected children in Africa.
Bwakura-Dangarembizi M, Kendall L, Bakeera-Kitaka S, Nahirya-Ntege P, Keishanyu R, Nathoo K, Spyer MJ, Kekitiinwa A, Lutaakome J, Mhute T, Kasirye P, Munderi P, Musiime V, Gibb DM, Walker AS, Prendergast AJ. Bwakura-Dangarembizi M, et al. N Engl J Med. 2014 Jan 2;370(1):41-53. doi: 10.1056/NEJMoa1214901. N Engl J Med. 2014. PMID: 24382064 Free PMC article. Clinical Trial.