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Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST.
Hum Mol Genet. 2016 Oct 15;25(20):4448-4461. doi: 10.1093/hmg/ddw274.
Hum Mol Genet. 2016.
PMID: 28173092
Free PMC article.
β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations.
Clarkson YL, Perkins EM, Cairncross CJ, Lyndon AR, Skehel PA, Jackson M.
Clarkson YL, et al.
Hum Mol Genet. 2014 Jul 15;23(14):3875-82. doi: 10.1093/hmg/ddu103. Epub 2014 Mar 6.
Hum Mol Genet. 2014.
PMID: 24603075
Free PMC article.
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Control of synaptic vesicle endocytosis by an extracellular signalling molecule.
Smillie KJ, Pawson J, Perkins EM, Jackson M, Cousin MA.
Smillie KJ, et al.
Nat Commun. 2013;4:2394. doi: 10.1038/ncomms3394.
Nat Commun. 2013.
PMID: 23999152
Free PMC article.
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