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Both RyRs and TPCs are required for NAADP-induced intracellular Ca²⁺ release.
Cell Calcium. 2015 Sep;58(3):237-45. doi: 10.1016/j.ceca.2015.05.005. Epub 2015 Jun 10.
Cell Calcium. 2015.
PMID: 26100948
Free PMC article.
Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells.
Ruas M, Davis LC, Chen CC, Morgan AJ, Chuang KT, Walseth TF, Grimm C, Garnham C, Powell T, Platt N, Platt FM, Biel M, Wahl-Schott C, Parrington J, Galione A.
Ruas M, et al.
EMBO J. 2015 Jul 2;34(13):1743-58. doi: 10.15252/embj.201490009. Epub 2015 Apr 14.
EMBO J. 2015.
PMID: 25872774
Free PMC article.
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