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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2009 | 2 |
2010 | 1 |
2012 | 1 |
2013 | 3 |
2014 | 2 |
2017 | 1 |
2024 | 0 |
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7 results
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Page 1
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need.
Nat Rev Microbiol. 2017 Feb 27;15(4):217-231. doi: 10.1038/nrmicro.2016.193. Online ahead of print.
Nat Rev Microbiol. 2017.
PMID: 28239154
Free PMC article.
Review.
The design and synthesis of potent and selective inhibitors of Trypanosoma brucei glycogen synthase kinase 3 for the treatment of human african trypanosomiasis.
Urich R, Grimaldi R, Luksch T, Frearson JA, Brenk R, Wyatt PG.
Urich R, et al.
J Med Chem. 2014 Sep 25;57(18):7536-49. doi: 10.1021/jm500239b. Epub 2014 Sep 8.
J Med Chem. 2014.
PMID: 25198388
Free PMC article.
Item in Clipboard
Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase.
Urbaniak MD, Capes AS, Crossman A, O'Neill S, Thompson S, Gilbert IH, Ferguson MA.
Urbaniak MD, et al.
Carbohydr Res. 2014 Mar 31;387(100):54-8. doi: 10.1016/j.carres.2013.12.016. Epub 2013 Dec 30.
Carbohydr Res. 2014.
PMID: 24589444
Free PMC article.
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The R enantiomer of the antitubercular drug PA-824 as a potential oral treatment for visceral Leishmaniasis.
Patterson S, Wyllie S, Stojanovski L, Perry MR, Simeons FR, Norval S, Osuna-Cabello M, De Rycker M, Read KD, Fairlamb AH.
Patterson S, et al.
Antimicrob Agents Chemother. 2013 Oct;57(10):4699-706. doi: 10.1128/AAC.00722-13. Epub 2013 Jul 15.
Antimicrob Agents Chemother. 2013.
PMID: 23856774
Free PMC article.
Item in Clipboard
Assessing the essentiality of Leishmania donovani nitroreductase and its role in nitro drug activation.
Wyllie S, Patterson S, Fairlamb AH.
Wyllie S, et al.
Antimicrob Agents Chemother. 2013 Feb;57(2):901-6. doi: 10.1128/AAC.01788-12. Epub 2012 Dec 3.
Antimicrob Agents Chemother. 2013.
PMID: 23208716
Free PMC article.
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Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
Spinks D, Shanks EJ, Cleghorn LA, McElroy S, Jones D, James D, Fairlamb AH, Frearson JA, Wyatt PG, Gilbert IH.
Spinks D, et al.
ChemMedChem. 2009 Dec;4(12):2060-9. doi: 10.1002/cmdc.200900262.
ChemMedChem. 2009.
PMID: 19924760
Free PMC article.
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Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductase.
Shanks EJ, Ong HB, Robinson DA, Thompson S, Sienkiewicz N, Fairlamb AH, Frearson JA.
Shanks EJ, et al.
Anal Biochem. 2010 Jan 15;396(2):194-203. doi: 10.1016/j.ab.2009.09.003. Epub 2009 Sep 11.
Anal Biochem. 2010.
PMID: 19748480
Free PMC article.
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