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Year Number of Results
2018 3
2019 2
2020 4
2022 2
2023 3
2024 1

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13 results

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Page 1
Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes.
Gamez M, Elhegni HE, Fawaz S, Ho KH, Campbell NW, Copland DA, Onions KL, Butler MJ, Wasson EJ, Crompton M, Ramnath RD, Qiu Y, Yamaguchi Y, Arkill KP, Bates DO, Turnbull JE, Zubkova OV, Welsh GI, Atan D, Satchell SC, Foster RR. Gamez M, et al. Cardiovasc Diabetol. 2024 Feb 1;23(1):50. doi: 10.1186/s12933-024-02133-1. Cardiovasc Diabetol. 2024. PMID: 38302978 Free PMC article.
Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation.
Bowen EE, Hurcombe JA, Barrington F, Keir LS, Farmer LK, Wherlock MD, Ortiz-Sandoval CG, Bruno V, Bohorquez-Hernandez A, Diatlov D, Rostam-Shirazi N, Wells S, Stewart M, Teboul L, Lay AC, Butler MJ, Pope RJP, Larkai EMS, Morgan BP, Moppett J, Satchell SC, Welsh GI, Walker PD, Licht C, Saleem MA, Coward RJM. Bowen EE, et al. Med. 2023 Nov 10;4(11):761-777.e8. doi: 10.1016/j.medj.2023.09.002. Epub 2023 Oct 19. Med. 2023. PMID: 37863058 Free article.
Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx.
Crompton M, Ferguson JK, Ramnath RD, Onions KL, Ogier AS, Gamez M, Down CJ, Skinner L, Wong KH, Dixon LK, Sutak J, Harper SJ, Pontrelli P, Gesualdo L, Heerspink HL, Toto RD, Welsh GI, Foster RR, Satchell SC, Butler MJ. Crompton M, et al. JCI Insight. 2023 Mar 8;8(5):e154164. doi: 10.1172/jci.insight.154164. JCI Insight. 2023. PMID: 36749631 Free PMC article. Clinical Trial.
Reduced Glomerular Filtration in Diabetes Is Attributable to Loss of Density and Increased Resistance of Glomerular Endothelial Cell Fenestrations.
Finch NC, Fawaz SS, Neal CR, Butler MJ, Lee VK, Salmon AJ, Lay AC, Stevens M, Dayalan L, Band H, Mellor HH, Harper SJ, Shima DT, Welsh GI, Foster RR, Satchell SC. Finch NC, et al. J Am Soc Nephrol. 2022 Jun;33(6):1120-1136. doi: 10.1681/ASN.2021030294. Epub 2022 Mar 15. J Am Soc Nephrol. 2022. PMID: 35292439 Free PMC article.
A role for NPY-NPY2R signaling in albuminuric kidney disease.
Lay AC, Barrington AF, Hurcombe JA, Ramnath RD, Graham M, Lewis PA, Wilson MC, Heesom KJ, Butler MJ, Perrett RM, Neal CR, Herbert E, Mountjoy E, Atan D, Nair V, Ju W, Nelson RG, Kretzler M, Satchell SC, McArdle CA, Welsh GI, Coward RJM. Lay AC, et al. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15862-15873. doi: 10.1073/pnas.2004651117. Epub 2020 Jun 19. Proc Natl Acad Sci U S A. 2020. PMID: 32561647 Free PMC article.
Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease.
Ramnath RD, Butler MJ, Newman G, Desideri S, Russell A, Lay AC, Neal CR, Qiu Y, Fawaz S, Onions KL, Gamez M, Crompton M, Michie C, Finch N, Coward RJ, Welsh GI, Foster RR, Satchell SC. Ramnath RD, et al. Kidney Int. 2020 May;97(5):951-965. doi: 10.1016/j.kint.2019.09.035. Epub 2019 Nov 2. Kidney Int. 2020. PMID: 32037077 Free PMC article.
13 results