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S(+)-(2E)-N-(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy.
Gunia-Krzyżak A, Żesławska E, Słoczyńska K, Żelaszczyk D, Sowa A, Koczurkiewicz-Adamczyk P, Popiół J, Nitek W, Pękala E, Marona H. Gunia-Krzyżak A, et al. Among authors: zelaszczyk d. Int J Mol Sci. 2020 Jun 19;21(12):4372. doi: 10.3390/ijms21124372. Int J Mol Sci. 2020. PMID: 32575479 Free PMC article.
Discovery of Novel UV-Filters with Favorable Safety Profiles in the 5-Arylideneimidazolidine-2,4-dione Derivatives Group.
Popiół J, Gunia-Krzyżak A, Piska K, Żelaszczyk D, Koczurkiewicz P, Słoczyńska K, Wójcik-Pszczoła K, Krupa A, Kryczyk-Poprawa A, Żesławska E, Nitek W, Żmudzki P, Marona H, Pękala E. Popiół J, et al. Among authors: zelaszczyk d. Molecules. 2019 Jun 24;24(12):2321. doi: 10.3390/molecules24122321. Molecules. 2019. PMID: 31238526 Free PMC article.
Metabolic stability and its role in the discovery of new chemical entities.
Słoczyńska K, Gunia-Krzyżak A, Koczurkiewicz P, Wójcik-Pszczoła K, Żelaszczyk D, Popiół J, Pękala E. Słoczyńska K, et al. Among authors: zelaszczyk d. Acta Pharm. 2019 Sep 1;69(3):345-361. doi: 10.2478/acph-2019-0024. Acta Pharm. 2019. PMID: 31259741 Free article. Review.
Anticonvulsant and analgesic in neuropathic pain activity in a group of new aminoalkanol derivatives.
Pańczyk K, Rapacz A, Furgała-Wojas A, Sałat K, Koczurkiewicz-Adamczyk P, Łucjanek M, Skiba-Kurek I, Karczewska E, Sowa A, Żelaszczyk D, Siwek A, Popiół J, Pękala E, Marona H, Waszkielewicz A. Pańczyk K, et al. Among authors: zelaszczyk d. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127325. doi: 10.1016/j.bmcl.2020.127325. Epub 2020 Jun 7. Bioorg Med Chem Lett. 2020. PMID: 32631530
Anticonvulsant activity, crystal structures, and preliminary safety evaluation of N-trans-cinnamoyl derivatives of selected (un)modified aminoalkanols.
Gunia-Krzyżak A, Żesławska E, Słoczyńska K, Koczurkiewicz P, Nitek W, Żelaszczyk D, Szkaradek N, Waszkielewicz AM, Pękala E, Marona H. Gunia-Krzyżak A, et al. Among authors: zelaszczyk d. Eur J Med Chem. 2016 Jan 1;107:26-37. doi: 10.1016/j.ejmech.2015.10.051. Epub 2015 Nov 2. Eur J Med Chem. 2016. PMID: 26560050
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3.
Gunia-Krzyżak A, Żelaszczyk D, Rapacz A, Żesławska E, Waszkielewicz AM, Pańczyk K, Słoczyńska K, Pękala E, Nitek W, Filipek B, Marona H. Gunia-Krzyżak A, et al. Among authors: zelaszczyk d. Bioorg Med Chem. 2017 Jan 15;25(2):471-482. doi: 10.1016/j.bmc.2016.11.014. Epub 2016 Nov 11. Bioorg Med Chem. 2017. PMID: 27876250
31 results