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Synthesis and anti-human immunodeficiency virus activity of substituted ( o,o-difluorophenyl)-linked-pyrimidines as potent non-nucleoside reverse transcriptase inhibitors.
Čechová L, Dejmek M, Baszczyňski O, Šaman D, Gao L, Hu E, Stepan G, Jansa P, Janeba Z, Šimon P. Čechová L, et al. Among authors: simon p. Antivir Chem Chemother. 2019 Jan-Dec;27:2040206619826265. doi: 10.1177/2040206619826265. Antivir Chem Chemother. 2019. PMID: 30788976 Free PMC article.
MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Vande Walle L, Stowe IB, Šácha P, Lee BL, Demon D, Fossoul A, Van Hauwermeiren F, Saavedra PHV, Šimon P, Šubrt V, Kostka L, Stivala CE, Pham VC, Staben ST, Yamazoe S, Konvalinka J, Kayagaki N, Lamkanfi M. Vande Walle L, et al. Among authors: simon p. PLoS Biol. 2019 Sep 16;17(9):e3000354. doi: 10.1371/journal.pbio.3000354. eCollection 2019 Sep. PLoS Biol. 2019. PMID: 31525186 Free PMC article.
Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.
Neburkova J, Sedlak F, Zackova Suchanova J, Kostka L, Sacha P, Subr V, Etrych T, Simon P, Barinkova J, Krystufek R, Spanielova H, Forstova J, Konvalinka J, Cigler P. Neburkova J, et al. Among authors: simon p. Mol Pharm. 2018 Aug 6;15(8):2932-2945. doi: 10.1021/acs.molpharmaceut.7b00889. Epub 2018 Feb 13. Mol Pharm. 2018. PMID: 29389139
2,447 results