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Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Alić I, Goh PA, Murray A, Portelius E, Gkanatsiou E, Gough G, Mok KY, Koschut D, Brunmeir R, Yeap YJ, O'Brien NL, Groet J, Shao X, Havlicek S, Dunn NR, Kvartsberg H, Brinkmalm G, Hithersay R, Startin C, Hamburg S, Phillips M, Pervushin K, Turmaine M, Wallon D, Rovelet-Lecrux A, Soininen H, Volpi E, Martin JE, Foo JN, Becker DL, Rostagno A, Ghiso J, Krsnik Ž, Šimić G, Kostović I, Mitrečić D; LonDownS Consortium; Francis PT, Blennow K, Strydom A, Hardy J, Zetterberg H, Nižetić D. Alić I, et al. Among authors: simic g. Mol Psychiatry. 2021 Oct;26(10):5766-5788. doi: 10.1038/s41380-020-0806-5. Epub 2020 Jul 10. Mol Psychiatry. 2021. PMID: 32647257 Free PMC article.
Does Alzheimer's disease begin in the brainstem?
Simic G, Stanic G, Mladinov M, Jovanov-Milosevic N, Kostovic I, Hof PR. Simic G, et al. Neuropathol Appl Neurobiol. 2009 Dec;35(6):532-54. doi: 10.1111/j.1365-2990.2009.01038.x. Epub 2009 Aug 4. Neuropathol Appl Neurobiol. 2009. PMID: 19682326 Free PMC article.
Extraordinary neoteny of synaptic spines in the human prefrontal cortex.
Petanjek Z, Judaš M, Šimic G, Rasin MR, Uylings HB, Rakic P, Kostovic I. Petanjek Z, et al. Among authors: simic g. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13281-6. doi: 10.1073/pnas.1105108108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788513 Free PMC article.
103 results