Šesták S - Search Results

1

'Click chemistry' synthesis of 1-(α-D-mannopyranosyl)-1,2,3-triazoles for inhibition of α-mannosidases.

Poláková M, Stanton R, Wilson IB, Holková I, Šesták S, Machová E, Jandová Z, Kóňa J. Poláková M, et al. Among authors: sestak s. Carbohydr Res. 2015 Apr 10;406:34-40. doi: 10.1016/j.carres.2015.01.004. Epub 2015 Jan 19. Carbohydr Res. 2015. PMID: 25658064 Free PMC article.

2

α-D-mannose derivatives as models designed for selective inhibition of Golgi α-mannosidase II.

Poláková M, Šesták S, Lattová E, Petruš L, Mucha J, Tvaroška I, Kóňa J. Poláková M, et al. Among authors: sestak s. Eur J Med Chem. 2011 Mar;46(3):944-52. doi: 10.1016/j.ejmech.2011.01.012. Epub 2011 Jan 15. Eur J Med Chem. 2011. PMID: 21295890

3

Expression, purification and preliminary crystallographic analysis of Drosophila melanogaster lysosomal α-mannosidase.

Nemčovičová I, Nemčovič M, Sesták S, Plšková M, Wilson IB, Mucha J. Nemčovičová I, et al. Among authors: sestak s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):965-70. doi: 10.1107/S1744309112029375. Epub 2012 Jul 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22869134 Free PMC article.

4

Characterisation of class I and II α-mannosidases from Drosophila melanogaster.

Nemčovičová I, Šesták S, Rendić D, Plšková M, Mucha J, Wilson IB. Nemčovičová I, et al. Among authors: sestak s. Glycoconj J. 2013 Dec;30(9):899-909. doi: 10.1007/s10719-013-9495-5. Epub 2013 Aug 25. Glycoconj J. 2013. PMID: 23979800

5

Synthesis of modified D-mannose core derivatives and their impact on GH38 α-mannosidases.

Poláková M, Horák R, Šesták S, Holková I. Poláková M, et al. Among authors: sestak s. Carbohydr Res. 2016 Jun 16;428:62-71. doi: 10.1016/j.carres.2016.04.004. Epub 2016 Apr 11. Carbohydr Res. 2016. PMID: 27152630

6

Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases.

Mirabella S, D'Adamio G, Matassini C, Goti A, Delgado S, Gimeno A, Robina I, Moreno-Vargas AJ, Šesták S, Jiménez-Barbero J, Cardona F. Mirabella S, et al. Among authors: sestak s. Chemistry. 2017 Oct 17;23(58):14585-14596. doi: 10.1002/chem.201703011. Epub 2017 Sep 13. Chemistry. 2017. PMID: 28902965

7

N-Benzyl Substitution of Polyhydroxypyrrolidines: The Way to Selective Inhibitors of Golgi α-Mannosidase II.

Šesták S, Bella M, Klunda T, Gurská S, Džubák P, Wöls F, Wilson IBH, Sladek V, Hajdúch M, Poláková M, Kóňa J. Šesták S, et al. ChemMedChem. 2018 Feb 20;13(4):373-383. doi: 10.1002/cmdc.201700607. Epub 2018 Feb 6. ChemMedChem. 2018. PMID: 29323461 Free PMC article.

8

Synthesis of 1,4-imino-L-lyxitols modified at C-5 and their evaluation as inhibitors of GH38 α-mannosidases.

Bella M, Šesták S, Moncoľ J, Koóš M, Poláková M. Bella M, et al. Among authors: sestak s. Beilstein J Org Chem. 2018 Aug 17;14:2156-2162. doi: 10.3762/bjoc.14.189. eCollection 2018. Beilstein J Org Chem. 2018. PMID: 30202468 Free PMC article.

9

Synthesis of N-benzyl substituted 1,4-imino-l-lyxitols with a basic functional group as selective inhibitors of Golgi α-mannosidase IIb.

Klunda T, Šesták S, Kóňa J, Poláková M. Klunda T, et al. Among authors: sestak s. Bioorg Chem. 2019 Mar;83:424-431. doi: 10.1016/j.bioorg.2018.10.066. Epub 2018 Oct 31. Bioorg Chem. 2019. PMID: 30428432

10

Synthesis and mannosidase inhibitory profile of a small library of aminocyclitols from shikimic acid-derived scaffolds.

Široký M, Gonda J, Martinková M, Jacková D, Vilková M, Bindzár V, Kuchár J, Šesták S. Široký M, et al. Among authors: sestak s. Carbohydr Res. 2020 Jul;493:108027. doi: 10.1016/j.carres.2020.108027. Epub 2020 May 11. Carbohydr Res. 2020. PMID: 32445981

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