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Novel butanehydrazide derivatives of purine-2,6-dione as dual PDE4/7 inhibitors with potential anti-inflammatory activity: Design, synthesis and biological evaluation.
Chłoń-Rzepa G, Jankowska A, Ślusarczyk M, Świerczek A, Pociecha K, Wyska E, Bucki A, Gawalska A, Kołaczkowski M, Pawłowski M. Chłoń-Rzepa G, et al. Among authors: swierczek a. Eur J Med Chem. 2018 Feb 25;146:381-394. doi: 10.1016/j.ejmech.2018.01.068. Epub 2018 Feb 4. Eur J Med Chem. 2018. PMID: 29407965
Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain.
Chłoń-Rzepa G, Ślusarczyk M, Jankowska A, Gawalska A, Bucki A, Kołaczkowski M, Świerczek A, Pociecha K, Wyska E, Zygmunt M, Kazek G, Sałat K, Pawłowski M. Chłoń-Rzepa G, et al. Among authors: swierczek a. Eur J Med Chem. 2018 Oct 5;158:517-533. doi: 10.1016/j.ejmech.2018.09.021. Epub 2018 Sep 10. Eur J Med Chem. 2018. PMID: 30245393
Novel phosphodiesterases inhibitors from the group of purine-2,6-dione derivatives as potent modulators of airway smooth muscle cell remodelling.
Wójcik-Pszczoła K, Chłoń-Rzepa G, Jankowska A, Ellen E, Świerczek A, Pociecha K, Koczurkiewicz P, Piska K, Gawędzka A, Wyska E, Knapik-Czajka M, Pękala E, Gosens R. Wójcik-Pszczoła K, et al. Among authors: swierczek a. Eur J Pharmacol. 2019 Dec 15;865:172779. doi: 10.1016/j.ejphar.2019.172779. Epub 2019 Nov 6. Eur J Pharmacol. 2019. PMID: 31705904
28 results