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MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.
Sanjiv K, Calderón-Montaño JM, Pham TM, Erkers T, Tsuber V, Almlöf I, Höglund A, Heshmati Y, Seashore-Ludlow B, Nagesh Danda A, Gad H, Wiita E, Göktürk C, Rasti A, Friedrich S, Centio A, Estruch M, Våtsveen TK, Struyf N, Visnes T, Scobie M, Koolmeister T, Henriksson M, Wallner O, Sandvall T, Lehmann S, Theilgaard-Mönch K, Garnett MJ, Östling P, Walfridsson J, Helleday T, Warpman Berglund U. Sanjiv K, et al. Among authors: ostling p. Cancer Res. 2021 Nov 15;81(22):5733-5744. doi: 10.1158/0008-5472.CAN-21-0061. Epub 2021 Sep 30. Cancer Res. 2021. PMID: 34593524 Free PMC article.
The transcriptome-wide landscape of molecular subtype-specific mRNA expression profiles in acute myeloid leukemia.
Mou T, Pawitan Y, Stahl M, Vesterlund M, Deng W, Jafari R, Bohlin A, Österroos A, Siavelis L, Bäckvall H, Erkers T, Kiviluoto S, Seashore-Ludlow B, Östling P, Orre LM, Kallioniemi O, Lehmann S, Lehtiö J, Vu TN. Mou T, et al. Among authors: ostling p. Am J Hematol. 2021 May 1;96(5):580-588. doi: 10.1002/ajh.26141. Epub 2021 Mar 10. Am J Hematol. 2021. PMID: 33625756 Free article.
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Leo IR, Aswad L, Stahl M, Kunold E, Post F, Erkers T, Struyf N, Mermelekas G, Joshi RN, Gracia-Villacampa E, Östling P, Kallioniemi OP, Tamm KP, Siavelis I, Lehtiö J, Vesterlund M, Jafari R. Leo IR, et al. Among authors: ostling p. Nat Commun. 2022 Mar 30;13(1):1691. doi: 10.1038/s41467-022-29224-5. Nat Commun. 2022. PMID: 35354797 Free PMC article.
Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip.
Sandström N, Carannante V, Olofsson K, Sandoz PA, Moussaud-Lamodière EL, Seashore-Ludlow B, Van Ooijen H, Verron Q, Frisk T, Takai M, Wiklund M, Östling P, Önfelt B. Sandström N, et al. Among authors: ostling p. Cell Rep Methods. 2022 Jul 18;2(7):100256. doi: 10.1016/j.crmeth.2022.100256. eCollection 2022 Jul 18. Cell Rep Methods. 2022. PMID: 35880015 Free PMC article.
Targeting SAMHD1 with hydroxyurea in first-line cytarabine-based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT-AML trial.
Jädersten M, Lilienthal I, Tsesmetzis N, Lourda M, Bengtzén S, Bohlin A, Arnroth C, Erkers T, Seashore-Ludlow B, Giraud G, Barkhordar GS, Tao S, Fogelstrand L, Saft L, Östling P, Schinazi RF, Kim B, Schaller T, Juliusson G, Deneberg S, Lehmann S, Rassidakis GZ, Höglund M, Henter JI, Herold N. Jädersten M, et al. Among authors: ostling p. J Intern Med. 2022 Dec;292(6):925-940. doi: 10.1111/joim.13553. Epub 2022 Aug 18. J Intern Med. 2022. PMID: 35934913 Free PMC article. Clinical Trial.
Prediction model for drug response of acute myeloid leukemia patients.
Trac QT, Pawitan Y, Mou T, Erkers T, Östling P, Bohlin A, Österroos A, Vesterlund M, Jafari R, Siavelis I, Bäckvall H, Kiviluoto S, Orre LM, Rantalainen M, Lehtiö J, Lehmann S, Kallioniemi O, Vu TN. Trac QT, et al. Among authors: ostling p. NPJ Precis Oncol. 2023 Mar 24;7(1):32. doi: 10.1038/s41698-023-00374-z. NPJ Precis Oncol. 2023. PMID: 36964195 Free PMC article.
The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients.
Åkerlund E, Gudoityte G, Moussaud-Lamodière E, Lind O, Bwanika HC, Lehti K, Salehi S, Carlson J, Wallin E, Fernebro J, Östling P, Kallioniemi O, Joneborg U, Seashore-Ludlow B. Åkerlund E, et al. Among authors: ostling p. NPJ Precis Oncol. 2023 Oct 31;7(1):111. doi: 10.1038/s41698-023-00463-z. NPJ Precis Oncol. 2023. PMID: 37907613 Free PMC article.
Delineating functional and molecular impact of ex vivo sample handling in precision medicine.
Struyf N, Österroos A, Vesterlund M, Arnroth C, James T, Sunandar S, Mermelekas G, Bohlin A, Hamberg Levedahl K, Bengtzén S, Jafari R, Orre LM, Lehtiö J, Lehmann S, Östling P, Kallioniemi O, Seashore-Ludlow B, Erkers T. Struyf N, et al. Among authors: ostling p. NPJ Precis Oncol. 2024 Feb 19;8(1):38. doi: 10.1038/s41698-024-00528-7. NPJ Precis Oncol. 2024. PMID: 38374206 Free PMC article.
42 results