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Nitric oxide is reduced to HNO by proton-coupled nucleophilic attack by ascorbate, tyrosine, and other alcohols. A new route to HNO in biological media?
Suarez SA, Neuman NI, Muñoz M, Álvarez L, Bikiel DE, Brondino CD, Ivanović-Burmazović I, Miljkovic JLj, Filipovic MR, Martí MA, Doctorovich F. Suarez SA, et al. Among authors: alvarez l. J Am Chem Soc. 2015 Apr 15;137(14):4720-7. doi: 10.1021/ja512343w. Epub 2015 Apr 2. J Am Chem Soc. 2015. PMID: 25773518
HNO Is Produced by the Reaction of NO with Thiols.
Suarez SA, Muñoz M, Alvarez L, Venâncio MF, Rocha WR, Bikiel DE, Marti MA, Doctorovich F. Suarez SA, et al. Among authors: alvarez l. J Am Chem Soc. 2017 Oct 18;139(41):14483-14487. doi: 10.1021/jacs.7b06968. Epub 2017 Oct 4. J Am Chem Soc. 2017. PMID: 28926245
The reactions of hydropersulfides (RSSH) with myoglobin.
Álvarez L, Suarez Vega V, McGinity C, Khodade VS, Toscano JP, Nagy P, Lin J, Works C, Fukuto JM. Álvarez L, et al. Arch Biochem Biophys. 2020 Jul 15;687:108391. doi: 10.1016/j.abb.2020.108391. Epub 2020 Apr 29. Arch Biochem Biophys. 2020. PMID: 32360749 Free article.
Cysteine Trisulfide Protects E. coli from Electrophile-Induced Death through the Generation of Cysteine Hydropersulfide.
Henderson CF, Bica I, Long FT, Irwin DD, Stull CH, Baker BW, Suarez Vega V, Taugher ZM, Fletes ED, Bartleson JM, Humphrey ML, Álvarez L, Akiyama M, Kumagai Y, Fukuto JM, Lin J. Henderson CF, et al. Among authors: alvarez l. Chem Res Toxicol. 2020 Feb 17;33(2):678-686. doi: 10.1021/acs.chemrestox.9b00494. Epub 2020 Jan 31. Chem Res Toxicol. 2020. PMID: 31977195
1,493 results