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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2017 | 1 |
2021 | 1 |
2022 | 2 |
2023 | 1 |
2024 | 1 |
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Page 1
WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells.
Nat Commun. 2021 Nov 12;12(1):6561. doi: 10.1038/s41467-021-26811-w.
Nat Commun. 2021.
PMID: 34772932
Free PMC article.
Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism.
Awate S, Brosh RM Jr.
Awate S, et al.
Int J Mol Sci. 2017 Jun 8;18(6):1233. doi: 10.3390/ijms18061233.
Int J Mol Sci. 2017.
PMID: 28594346
Free PMC article.
Review.
Item in Clipboard
Replication stress as a driver of cellular senescence and aging.
Herr LM, Schaffer ED, Fuchs KF, Datta A, Brosh RM Jr.
Herr LM, et al.
Commun Biol. 2024 May 22;7(1):616. doi: 10.1038/s42003-024-06263-w.
Commun Biol. 2024.
PMID: 38777831
Free PMC article.
Review.
Item in Clipboard
Discovery of a new hereditary RECQ helicase disorder RECON syndrome positions the replication stress response and genome homeostasis as centrally important processes in aging and age-related disease.
Datta A, Sommers JA, Jhujh SS, Harel T, Stewart GS, Brosh RM Jr.
Datta A, et al.
Ageing Res Rev. 2023 Apr;86:101887. doi: 10.1016/j.arr.2023.101887. Epub 2023 Feb 19.
Ageing Res Rev. 2023.
PMID: 36805074
Free PMC article.
Review.
Item in Clipboard
DNA fiber analyses to study functional importance of helicases and associated factors during replication stress.
Datta A, Brosh RM Jr.
Datta A, et al.
Methods Enzymol. 2022;672:153-171. doi: 10.1016/bs.mie.2022.04.003. Epub 2022 Apr 28.
Methods Enzymol. 2022.
PMID: 35934474
Item in Clipboard
WRN rescues replication forks compromised by a BRCA2 deficiency: Predictions for how inhibition of a helicase that suppresses premature aging tilts the balance to fork demise and chromosomal instability in cancer.
Datta A, Brosh RM Jr.
Datta A, et al.
Bioessays. 2022 Aug;44(8):e2200057. doi: 10.1002/bies.202200057. Epub 2022 Jun 25.
Bioessays. 2022.
PMID: 35751457
Free PMC article.
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