Z01 BC010030/ImNIH/Intramural NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2011	2
2015	3
2016	1
2017	4
2018	3
2019	4
2020	2
2021	3
2022	2
2023	1
2024	1

1

Discovering natural product modulators to overcome multidrug resistance in cancer chemotherapy.

Wu CP, Ohnuma S, Ambudkar SV. Wu CP, et al. Curr Pharm Biotechnol. 2011 Apr;12(4):609-20. doi: 10.2174/138920111795163887. Curr Pharm Biotechnol. 2011. PMID: 21118092 Free PMC article. Review.

2

Natural medicinal compounds target signal transduction pathways to overcome ABC drug efflux transporter-mediated multidrug resistance in cancer.

Bharathiraja P, Yadav P, Sajid A, Ambudkar SV, Prasad NR. Bharathiraja P, et al. Drug Resist Updat. 2023 Nov;71:101004. doi: 10.1016/j.drup.2023.101004. Epub 2023 Aug 21. Drug Resist Updat. 2023. PMID: 37660590 Review.

3

Interaction of A₃ adenosine receptor ligands with the human multidrug transporter ABCG2.

Abel B, Murakami M, Tosh DK, Yu J, Lusvarghi S, Campbell RG, Gao ZG, Jacobson KA, Ambudkar SV. Abel B, et al. Eur J Med Chem. 2022 Mar 5;231:114103. doi: 10.1016/j.ejmech.2022.114103. Epub 2022 Jan 10. Eur J Med Chem. 2022. PMID: 35152062 Free PMC article.

4

Improving cancer chemotherapy with modulators of ABC drug transporters.

Shukla S, Ohnuma S, Ambudkar SV. Shukla S, et al. Curr Drug Targets. 2011 May;12(5):621-30. doi: 10.2174/138945011795378540. Curr Drug Targets. 2011. PMID: 21039338 Free PMC article. Review.

5

Polyoxovanadates as new P-glycoprotein inhibitors: insights into the mechanism of inhibition.

Kita DH, de Andrade GA, Missina JM, Postal K, Boell VK, Santana FS, Zattoni IF, Zanzarini IDS, Moure VR, Rego FGM, Picheth G, de Souza EM, Mitchell DA, Ambudkar SV, Nunes GG, Valdameri G. Kita DH, et al. FEBS Lett. 2022 Feb;596(3):381-399. doi: 10.1002/1873-3468.14265. Epub 2021 Dec 30. FEBS Lett. 2022. PMID: 34939198 Free PMC article.

6

Molecular basis of the polyspecificity of P-glycoprotein (ABCB1): recent biochemical and structural studies.

Chufan EE, Sim HM, Ambudkar SV. Chufan EE, et al. Adv Cancer Res. 2015;125:71-96. doi: 10.1016/bs.acr.2014.10.003. Epub 2015 Jan 8. Adv Cancer Res. 2015. PMID: 25640267 Free PMC article. Review.

7

ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators.

Lusvarghi S, Ambudkar SV. Lusvarghi S, et al. Biochem J. 2019 Dec 19;476(24):3737-3750. doi: 10.1042/BCJ20190736. Biochem J. 2019. PMID: 31774117 Free PMC article.

8

Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs.

Wu CP, Lusvarghi S, Hsiao SH, Liu TC, Li YQ, Huang YH, Hung TH, Ambudkar SV. Wu CP, et al. J Nat Prod. 2020 May 22;83(5):1461-1472. doi: 10.1021/acs.jnatprod.9b01022. Epub 2020 Apr 29. J Nat Prod. 2020. PMID: 32347726 Free PMC article.

9

Regorafenib antagonizes BCRP-mediated multidrug resistance in colon cancer.

Zhang YK, Wang YJ, Lei ZN, Zhang GN, Zhang XY, Wang DS, Al-Rihani SB, Shukla S, Ambudkar SV, Kaddoumi A, Shi Z, Chen ZS. Zhang YK, et al. Cancer Lett. 2019 Feb 1;442:104-112. doi: 10.1016/j.canlet.2018.10.032. Epub 2018 Oct 28. Cancer Lett. 2019. PMID: 30392788 Free PMC article.

10

Selective reversal of BCRP-mediated MDR by VEGFR-2 inhibitor ZM323881.

Zhang YK, Zhang XY, Zhang GN, Wang YJ, Xu H, Zhang D, Shukla S, Liu L, Yang DH, Ambudkar SV, Chen ZS. Zhang YK, et al. Biochem Pharmacol. 2017 May 15;132:29-37. doi: 10.1016/j.bcp.2017.02.019. Epub 2017 Feb 27. Biochem Pharmacol. 2017. PMID: 28242251 Free PMC article.

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