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DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types.
Nat Commun. 2022 Sep 24;13(1):5620. doi: 10.1038/s41467-022-33394-7.
Nat Commun. 2022.
PMID: 36153390
Free PMC article.
Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles.
Hannon E, Dempster EL, Davies JP, Chioza B, Blake GET, Burrage J, Policicchio S, Franklin A, Walker EM, Bamford RA, Schalkwyk LC, Mill J.
Hannon E, et al.
BMC Biol. 2024 Jan 25;22(1):17. doi: 10.1186/s12915-024-01827-y.
BMC Biol. 2024.
PMID: 38273288
Free PMC article.
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