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2023 10
2024 1

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11 results

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Page 1
Pancreatic cancer: Advances and challenges.
Halbrook CJ, Lyssiotis CA, Pasca di Magliano M, Maitra A. Halbrook CJ, et al. Cell. 2023 Apr 13;186(8):1729-1754. doi: 10.1016/j.cell.2023.02.014. Cell. 2023. PMID: 37059070 Free PMC article. Review.
KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells.
Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Paradiso F, Sugimoto H, Arian KA, Ying H, Barekatain Y, Sthanam LK, Kelly PJ, Maitra A, Heffernan TP, Kalluri R. Mahadevan KK, et al. Cancer Cell. 2023 Sep 11;41(9):1606-1620.e8. doi: 10.1016/j.ccell.2023.07.002. Epub 2023 Aug 24. Cancer Cell. 2023. PMID: 37625401
Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions.
Carpenter ES, Elhossiny AM, Kadiyala P, Li J, McGue J, Griffith BD, Zhang Y, Edwards J, Nelson S, Lima F, Donahue KL, Du W, Bischoff AC, Alomari D, Watkoske HR, Mattea M, The S, Espinoza CE, Barrett M, Sonnenday CJ, Olden N, Chen CT, Peterson N, Gunchick V, Sahai V, Rao A, Bednar F, Shi J, Frankel TL, Pasca di Magliano M. Carpenter ES, et al. Cancer Discov. 2023 Jun 2;13(6):1324-1345. doi: 10.1158/2159-8290.CD-23-0013. Cancer Discov. 2023. PMID: 37021392 Free PMC article.
Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential.
Sans M, Makino Y, Min J, Rajapakshe KI, Yip-Schneider M, Schmidt CM, Hurd MW, Burks JK, Gomez JA, Thege FI, Fahrmann JF, Wolff RA, Kim MP, Guerrero PA, Maitra A. Sans M, et al. Cancer Discov. 2023 Aug 4;13(8):1844-1861. doi: 10.1158/2159-8290.CD-22-1200. Cancer Discov. 2023. PMID: 37285225 Free PMC article.
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces.
Deshpande A, Loth M, Sidiropoulos DN, Zhang S, Yuan L, Bell ATF, Zhu Q, Ho WJ, Santa-Maria C, Gilkes DM, Williams SR, Uytingco CR, Chew J, Hartnett A, Bent ZW, Favorov AV, Popel AS, Yarchoan M, Kiemen A, Wu PH, Fujikura K, Wirtz D, Wood LD, Zheng L, Jaffee EM, Anders RA, Danilova L, Stein-O'Brien G, Kagohara LT, Fertig EJ. Deshpande A, et al. Cell Syst. 2023 Apr 19;14(4):285-301.e4. doi: 10.1016/j.cels.2023.03.004. Cell Syst. 2023. PMID: 37080163 Free PMC article.
Converging on a Cure: The Roads to Predictive Immunotherapy.
Stein-O'Brien GL, Le DT, Jaffee EM, Fertig EJ, Zaidi N. Stein-O'Brien GL, et al. Cancer Discov. 2023 May 4;13(5):1053-1057. doi: 10.1158/2159-8290.CD-23-0277. Cancer Discov. 2023. PMID: 37067199 Free PMC article. Review.
Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project.
Semaan A, Bernard V, Wong J, Makino Y, Swartzlander DB, Rajapakshe KI, Lee JJ, Officer A, Schmidt CM, Wu HH, Scaife CL, Affolter KE, Nachmanson D, Firpo MA, Yip-Schneider M, Lowy AM, Harismendy O, Sen S, Maitra A, Jakubek YA, Guerrero PA. Semaan A, et al. Cancer Res Commun. 2023 Oct 10;3(10):2062-2073. doi: 10.1158/2767-9764.CRC-22-0419. Cancer Res Commun. 2023. PMID: 37721516 Free PMC article.
KRT17High/CXCL8+ tumor cells display both classical and basal features and regulate myeloid infiltration in the pancreatic cancer microenvironment.
Carpenter ES, Kadiyala P, Elhossiny AM, Kemp SB, Li J, Steele NG, Nicolle R, Nwosu ZC, Freeman J, Dai H, Paglia D, Du W, Donahue K, Morales J, Medina-Cabrera PI, Bonilla ME, Harris L, The S, Gunchick V, Peterson N, Brown K, Mattea M, Espinoza CE, McGue J, Kabala SM, Baliira RK, Renollet NM, Mooney AG, Liu J, Bhalla S, Farida JP, Ko C, Machicado JD, Kwon RS, Wamsteker EJ, Schulman A, Anderson MA, Law R, Prabhu A, Coulombe PA, Rao A, Frankel TL, Bednar F, Shi J, Sahai V, Pasca di Magliano M. Carpenter ES, et al. Clin Cancer Res. 2023 Oct 18:10.1158/1078-0432.CCR-23-1421. doi: 10.1158/1078-0432.CCR-23-1421. Online ahead of print. Clin Cancer Res. 2023. PMID: 37851080
11 results