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Page 1
Distinct viral reservoirs in individuals with spontaneous control of HIV-1.
Jiang C, Lian X, Gao C, Sun X, Einkauf KB, Chevalier JM, Chen SMY, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, Milush J, Bertagnolli LN, Sweet SE, Varriale JA, Burbelo PD, Chun TW, Laird GM, Serrao E, Engelman AN, Carrington M, Siliciano RF, Siliciano JM, Deeks SG, Walker BD, Lichterfeld M, Yu XG. Jiang C, et al. Nature. 2020 Sep;585(7824):261-267. doi: 10.1038/s41586-020-2651-8. Epub 2020 Aug 26. Nature. 2020. PMID: 32848246 Free PMC article.
Safety and Pharmacokinetics of Intravenous 10-1074 and VRC01LS in Young Children.
Capparelli EV, Ajibola G, Maswabi K, Holme MP, Bennett K, Powis KM, Moyo S, Mohammed T, Maphorisa C, Hughes MD, Seaton KE, Tomaras GD, Mosher S, Taylor A, O'Connell S, Narpala S, Mcdermott A, Caskey M, Gama L, Lockman S, Jean-Philippe P, Makhema J, Kuritzkes DR, Lichterfeld M, Shapiro RL; Tatelo Study Team. Capparelli EV, et al. J Acquir Immune Defic Syndr. 2022 Oct 1;91(2):182-188. doi: 10.1097/QAI.0000000000003033. J Acquir Immune Defic Syndr. 2022. PMID: 36094485 Free PMC article.
Broadly neutralizing antibody treatment maintained HIV suppression in children with favorable reservoir characteristics in Botswana.
Shapiro RL, Ajibola G, Maswabi K, Hughes M, Nelson BS, Niesar A, Pretorius Holme M, Powis KM, Sakoi M, Batlang O, Moyo S, Mohammed T, Maphorisa C, Bennett K, Hu Z, Giguel F, Reeves JD, Reeves MA, Gao C, Yu X, Ackerman ME, McDermott A, Cooper M, Caskey M, Gama L, Jean-Philippe P, Yin DE, Capparelli EV, Lockman S, Makhema J, Kuritzkes DR, Lichterfeld M. Shapiro RL, et al. Sci Transl Med. 2023 Jul 5;15(703):eadh0004. doi: 10.1126/scitranslmed.adh0004. Epub 2023 Jul 5. Sci Transl Med. 2023. PMID: 37406137 Free PMC article. Clinical Trial.
Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers.
Lian X, Gao C, Sun X, Jiang C, Einkauf KB, Seiger KW, Chevalier JM, Yuki Y, Martin M, Hoh R, Peluso MJ, Carrington M, Ruiz-Mateos E, Deeks SG, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG. Lian X, et al. Sci Transl Med. 2021 Dec 15;13(624):eabl4097. doi: 10.1126/scitranslmed.abl4097. Epub 2021 Dec 15. Sci Transl Med. 2021. PMID: 34910552 Free PMC article.
The HIV-1 reservoir landscape in persistent elite controllers and transient elite controllers.
Gasca-Capote C, Lian X, Gao C, Roseto IC, Jiménez-León MR, Gladkov G, Camacho-Sojo MI, Pérez-Gómez A, Gallego I, Lopez-Cortes LE, Bachiller S, Vitalle J, Rafii-El-Idrissi Benhnia M, Ostos FJ, Collado-Romacho AR, Santos J, Palacios R, Gomez-Ayerbe C, Muñoz-Medina L, Ruiz-Sancho A, Frias M, Rivero-Juarez A, Roca-Oporto C, Hidalgo-Tenorio C, Rull A, Olalla J, Lopez-Ruz MA, Vidal F, Viladés C, Mastrangelo A, Cavassini M, Espinosa N, Perreau M, Peraire J, Rivero A, López-Cortes LF, Lichterfeld M, Yu XG, Ruiz-Mateos E. Gasca-Capote C, et al. J Clin Invest. 2024 Feb 20;134(8):e174215. doi: 10.1172/JCI174215. J Clin Invest. 2024. PMID: 38376918 Free PMC article.
Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-α2a.
Armani-Tourret M, Gao C, Hartana CA, Sun W, Carrere L, Vela L, Hochroth A, Bellefroid M, Sbrolla A, Shea K, Flynn T, Roseto I, Rassadkina Y, Lee C, Giguel F, Malhotra R, Bushman FD, Gandhi RT, Yu XG, Kuritzkes DR, Lichterfeld M. Armani-Tourret M, et al. Cell. 2024 Feb 29;187(5):1238-1254.e14. doi: 10.1016/j.cell.2024.01.037. Epub 2024 Feb 17. Cell. 2024. PMID: 38367616 Free PMC article. Clinical Trial.
18 results