RE/08/004/23915/BHF_/British Heart Foundation/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2015	2
2016	2
2017	1
2018	2
2019	3
2020	3
2021	1
2022	1
2024	0

1

All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation.

Paci M, Passini E, Klimas A, Severi S, Hyttinen J, Rodriguez B, Entcheva E. Paci M, et al. Biophys J. 2020 May 19;118(10):2596-2611. doi: 10.1016/j.bpj.2020.03.018. Epub 2020 Apr 4. Biophys J. 2020. PMID: 32298635 Free PMC article.

2

Non-competitive cyclic peptides for targeting enzyme-substrate complexes.

McAllister TE, Yeh TL, Abboud MI, Leung IKH, Hookway ES, King ONF, Bhushan B, Williams ST, Hopkinson RJ, Münzel M, Loik ND, Chowdhury R, Oppermann U, Claridge TDW, Goto Y, Suga H, Schofield CJ, Kawamura A. McAllister TE, et al. Chem Sci. 2018 Apr 23;9(20):4569-4578. doi: 10.1039/c8sc00286j. eCollection 2018 May 28. Chem Sci. 2018. PMID: 29899950 Free PMC article.

3

Noninvasive In Vivo Assessment of Cardiac Metabolism in the Healthy and Diabetic Human Heart Using Hyperpolarized ¹³C MRI.

Rider OJ, Apps A, Miller JJJJ, Lau JYC, Lewis AJM, Peterzan MA, Dodd MS, Lau AZ, Trumper C, Gallagher FA, Grist JT, Brindle KM, Neubauer S, Tyler DJ. Rider OJ, et al. Circ Res. 2020 Mar 13;126(6):725-736. doi: 10.1161/CIRCRESAHA.119.316260. Epub 2020 Feb 5. Circ Res. 2020. PMID: 32078413 Free PMC article.

4

The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases.

Roatsch M, Hoffmann I, Abboud MI, Hancock RL, Tarhonskaya H, Hsu KF, Wilkins SE, Yeh TL, Lippl K, Serrer K, Moneke I, Ahrens TD, Robaa D, Wenzler S, Barthes NPF, Franz H, Sippl W, Lassmann S, Diederichs S, Schleicher E, Schofield CJ, Kawamura A, Schüle R, Jung M. Roatsch M, et al. ACS Chem Biol. 2019 Aug 16;14(8):1737-1750. doi: 10.1021/acschembio.9b00289. Epub 2019 Jul 19. ACS Chem Biol. 2019. PMID: 31287655

5

The Retinoid Agonist Tazarotene Promotes Angiogenesis and Wound Healing.

Al Haj Zen A, Nawrot DA, Howarth A, Caporali A, Ebner D, Vernet A, Schneider JE, Bhattacharya S. Al Haj Zen A, et al. Mol Ther. 2016 Oct;24(10):1745-1759. doi: 10.1038/mt.2016.153. Epub 2016 Aug 2. Mol Ther. 2016. PMID: 27480772 Free PMC article.

6

Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities.

Trovato C, Passini E, Nagy N, Varró A, Abi-Gerges N, Severi S, Rodriguez B. Trovato C, et al. J Mol Cell Cardiol. 2020 May;142:24-38. doi: 10.1016/j.yjmcc.2020.04.001. Epub 2020 Apr 3. J Mol Cell Cardiol. 2020. PMID: 32251669 Free PMC article.

7

In Vivo and In Silico Investigation Into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes.

Zhou X, Bueno-Orovio A, Orini M, Hanson B, Hayward M, Taggart P, Lambiase PD, Burrage K, Rodriguez B. Zhou X, et al. Circ Res. 2016 Jan 22;118(2):266-78. doi: 10.1161/CIRCRESAHA.115.307836. Epub 2015 Nov 24. Circ Res. 2016. PMID: 26602864 Free PMC article.

8

MicroRNA-148b Targets the TGF-β Pathway to Regulate Angiogenesis and Endothelial-to-Mesenchymal Transition during Skin Wound Healing.

Miscianinov V, Martello A, Rose L, Parish E, Cathcart B, Mitić T, Gray GA, Meloni M, Al Haj Zen A, Caporali A. Miscianinov V, et al. Mol Ther. 2018 Aug 1;26(8):1996-2007. doi: 10.1016/j.ymthe.2018.05.002. Epub 2018 May 8. Mol Ther. 2018. PMID: 29843955 Free PMC article.

9

Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations.

Sparrow AJ, Sievert K, Patel S, Chang YF, Broyles CN, Brook FA, Watkins H, Geeves MA, Redwood CS, Robinson P, Daniels MJ. Sparrow AJ, et al. Circ Res. 2019 Apr 12;124(8):1228-1239. doi: 10.1161/CIRCRESAHA.118.314600. Circ Res. 2019. PMID: 30732532 Free PMC article.

10

Human In Silico Drug Trials Demonstrate Higher Accuracy than Animal Models in Predicting Clinical Pro-Arrhythmic Cardiotoxicity.

Passini E, Britton OJ, Lu HR, Rohrbacher J, Hermans AN, Gallacher DJ, Greig RJH, Bueno-Orovio A, Rodriguez B. Passini E, et al. Front Physiol. 2017 Sep 12;8:668. doi: 10.3389/fphys.2017.00668. eCollection 2017. Front Physiol. 2017. PMID: 28955244 Free PMC article.

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