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Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus.
Xue M, Zhang Y, Wang H, Kairis EL, Lu M, Ahmad S, Attia Z, Harder O, Zhang Z, Wei J, Chen P, Gao Y, Peeples ME, Sharma A, Boyaka P, He C, Hur S, Niewiesk S, Li J. Xue M, et al. PLoS Pathog. 2021 Dec 20;17(12):e1010142. doi: 10.1371/journal.ppat.1010142. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34929018 Free PMC article.
5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons.
Zhang Y, Zhang LS, Dai Q, Chen P, Lu M, Kairis EL, Murugaiah V, Xu J, Shukla RK, Liang X, Zou Z, Cormet-Boyaka E, Qiu J, Peeples ME, Sharma A, He C, Li J. Zhang Y, et al. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2123338119. doi: 10.1073/pnas.2123338119. Epub 2022 Oct 14. Proc Natl Acad Sci U S A. 2022. PMID: 36240321 Free PMC article.
A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters.
Lu M, Zhang Y, Dravid P, Li A, Zeng C, Kc M, Trivedi S, Sharma H, Chaiwatpongsakorn S, Zani A, Kenney A, Cai C, Ye C, Liang X, Qiu J, Martinez-Sobrido L, Yount JS, Boyaka PN, Liu SL, Peeples ME, Kapoor A, Li J. Lu M, et al. J Virol. 2021 Sep 27;95(20):e0059221. doi: 10.1128/JVI.00592-21. Epub 2021 Aug 11. J Virol. 2021. PMID: 34379509 Free PMC article.
A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike.
Lu M, Dravid P, Zhang Y, Trivedi S, Li A, Harder O, Kc M, Chaiwatpongsakorn S, Zani A, Kenney A, Zeng C, Cai C, Ye C, Liang X, Shimamura M, Liu SL, Mejias A, Ramilo O, Boyaka PN, Qiu J, Martinez-Sobrido L, Yount JS, Peeples ME, Kapoor A, Niewiesk S, Li J. Lu M, et al. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2026153118. doi: 10.1073/pnas.2026153118. Proc Natl Acad Sci U S A. 2021. PMID: 33688034 Free PMC article.
14 results