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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2020 | 1 |
2021 | 3 |
2024 | 2 |
Search Results
6 results
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Page 1
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models.
Nat Commun. 2020 Jul 24;11(1):3726. doi: 10.1038/s41467-020-17127-2.
Nat Commun. 2020.
PMID: 32709856
Free PMC article.
CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models.
Xu H, George E, Kinose Y, Kim H, Shah JB, Peake JD, Ferman B, Medvedev S, Murtha T, Barger CJ, Devins KM, D'Andrea K, Wubbenhorst B, Schwartz LE, Hwang WT, Mills GB, Nathanson KL, Karpf AR, Drapkin R, Brown EJ, Simpkins F.
Xu H, et al.
Cell Rep Med. 2021 Sep 23;2(9):100394. doi: 10.1016/j.xcrm.2021.100394. eCollection 2021 Sep 21.
Cell Rep Med. 2021.
PMID: 34622231
Free PMC article.
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A B7-H4-Targeting Antibody-Drug Conjugate Shows Antitumor Activity in PARPi and Platinum-Resistant Cancers with B7-H4 Expression.
Gitto SB, Whicker M, Davies G, Kumar S, Kinneer K, Xu H, Lewis A, Mamidi S, Medvedev S, Kim H, Anderton J, Tang EJ, Ferman B, Coats S, Wilkinson RW, Brown E, Powell DJ Jr, Simpkins F.
Gitto SB, et al.
Clin Cancer Res. 2024 Apr 15;30(8):1567-1581. doi: 10.1158/1078-0432.CCR-23-1079.
Clin Cancer Res. 2024.
PMID: 37882675
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Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-resistant epithelial ovarian cancer.
Shah PD, Wethington SL, Pagan C, Latif N, Tanyi J, Martin LP, Morgan M, Burger RA, Haggerty A, Zarrin H, Rodriguez D, Domchek S, Drapkin R, Shih IM, Smith SA, Dean E, Gaillard S, Armstrong D, Torigian DA, Hwang WT, Giuntoli R, Simpkins F.
Shah PD, et al.
Gynecol Oncol. 2021 Nov;163(2):246-253. doi: 10.1016/j.ygyno.2021.08.024. Epub 2021 Oct 5.
Gynecol Oncol. 2021.
PMID: 34620496
Free PMC article.
Clinical Trial.
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Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR.
Xu H, George E, Gallo D, Medvedev S, Wang X, Kryczka R, Hyer ML, Fourtounis J, Stocco R, Aguado-Fraile E, Petrone A, Yin SY, Shiwram A, Anderson M, Kim H, Liu F, Marshall CG, Simpkins F.
Xu H, et al.
Res Sq [Preprint]. 2024 Feb 16:rs.3.rs-3854682. doi: 10.21203/rs.3.rs-3854682/v1.
Res Sq. 2024.
PMID: 38410486
Free PMC article.
Preprint.
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Induction of IL19 expression through JNK and cGAS-STING modulates DNA damage-induced cytokine production.
Small SH, Tang EJ, Ragland RL, Ruzankina Y, Schoppy DW, Mandal RS, Glineburg MR, Ustelenca Z, Powell DJ, Simpkins F, Johnson FB, Brown EJ.
Small SH, et al.
Sci Signal. 2021 Dec 21;14(714):eaba2611. doi: 10.1126/scisignal.aba2611. Epub 2021 Dec 21.
Sci Signal. 2021.
PMID: 34932373
Free PMC article.
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