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Dynamic equilibria in protein kinases.
Pegram LM, Anderson JW, Ahn NG. Pegram LM, et al. Curr Opin Struct Biol. 2021 Dec;71:215-222. doi: 10.1016/j.sbi.2021.07.006. Epub 2021 Aug 20. Curr Opin Struct Biol. 2021. PMID: 34425481 Free PMC article. Review.
Kinase Activation by Small Conformational Changes.
Lopez ED, Burastero O, Arcon JP, Defelipe LA, Ahn NG, Marti MA, Turjanski AG. Lopez ED, et al. J Chem Inf Model. 2020 Feb 24;60(2):821-832. doi: 10.1021/acs.jcim.9b00782. Epub 2019 Nov 27. J Chem Inf Model. 2020. PMID: 31714778 Free PMC article.
Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2.
Pegram LM, Liddle JC, Xiao Y, Hoh M, Rudolph J, Iverson DB, Vigers GP, Smith D, Zhang H, Wang W, Moffat JG, Ahn NG. Pegram LM, et al. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15463-15468. doi: 10.1073/pnas.1906824116. Epub 2019 Jul 16. Proc Natl Acad Sci U S A. 2019. PMID: 31311868 Free PMC article.
14 results