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Liver tumorigenesis is promoted by a high saturated fat diet specifically in male mice and is associated with hepatic expression of the proto-oncogene Agap2 and enrichment of the intestinal microbiome with Coprococcus.
Pedersen KB, Pulliam CF, Patel A, Del Piero F, Watanabe TTN, Wankhade UD, Shankar K, Hicks C, Ronis MJ. Pedersen KB, et al. Carcinogenesis. 2019 Apr 29;40(2):349-359. doi: 10.1093/carcin/bgy141. Carcinogenesis. 2019. PMID: 30325408 Free PMC article.
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