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Insights into distinct signaling profiles of the µOR activated by diverse agonists.
Qu Q, Huang W, Aydin D, Paggi JM, Seven AB, Wang H, Chakraborty S, Che T, DiBerto JF, Robertson MJ, Inoue A, Suomivuori CM, Roth BL, Majumdar S, Dror RO, Kobilka BK, Skiniotis G. Qu Q, et al. Nat Chem Biol. 2023 Apr;19(4):423-430. doi: 10.1038/s41589-022-01208-y. Epub 2022 Nov 21. Nat Chem Biol. 2023. PMID: 36411392 Free PMC article.
Oxidative Metabolism as a Modulator of Kratom's Biological Actions.
Chakraborty S, Uprety R, Slocum ST, Irie T, Le Rouzic V, Li X, Wilson LL, Scouller B, Alder AF, Kruegel AC, Ansonoff M, Varadi A, Eans SO, Hunkele A, Allaoa A, Kalra S, Xu J, Pan YX, Pintar J, Kivell BM, Pasternak GW, Cameron MD, McLaughlin JP, Sames D, Majumdar S. Chakraborty S, et al. J Med Chem. 2021 Nov 25;64(22):16553-16572. doi: 10.1021/acs.jmedchem.1c01111. Epub 2021 Nov 16. J Med Chem. 2021. PMID: 34783240 Free PMC article.
Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom.
Chakraborty S, Uprety R, Daibani AE, Rouzic VL, Hunkele A, Appourchaux K, Eans SO, Nuthikattu N, Jilakara R, Thammavong L, Pasternak GW, Pan YX, McLaughlin JP, Che T, Majumdar S. Chakraborty S, et al. ACS Chem Neurosci. 2021 Jul 21;12(14):2661-2678. doi: 10.1021/acschemneuro.1c00149. Epub 2021 Jul 2. ACS Chem Neurosci. 2021. PMID: 34213886 Free PMC article.
19 results