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Microglia use TAM receptors to detect and engulf amyloid β plaques.
Huang Y, Happonen KE, Burrola PG, O'Connor C, Hah N, Huang L, Nimmerjahn A, Lemke G. Huang Y, et al. Nat Immunol. 2021 May;22(5):586-594. doi: 10.1038/s41590-021-00913-5. Epub 2021 Apr 15. Nat Immunol. 2021. PMID: 33859405 Free PMC article.
TAM receptors regulate multiple features of microglial physiology.
Fourgeaud L, Través PG, Tufail Y, Leal-Bailey H, Lew ED, Burrola PG, Callaway P, Zagórska A, Rothlin CV, Nimmerjahn A, Lemke G. Fourgeaud L, et al. Nature. 2016 Apr 14;532(7598):240-244. doi: 10.1038/nature17630. Epub 2016 Apr 6. Nature. 2016. PMID: 27049947 Free PMC article.
Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery.
Hunter M, Spiller KJ, Dominique MA, Xu H, Hunter FW, Fang TC, Canter RG, Roberts CJ, Ransohoff RM, Trojanowski JQ, Lee VM. Hunter M, et al. Acta Neuropathol Commun. 2021 Aug 19;9(1):140. doi: 10.1186/s40478-021-01239-x. Acta Neuropathol Commun. 2021. PMID: 34412701 Free PMC article.
16 results