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Distinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support.
Circulation. 2023 Jan 31;147(5):409-424. doi: 10.1161/CIRCULATIONAHA.121.056600. Epub 2022 Nov 30.
Circulation. 2023.
PMID: 36448446
Free PMC article.
Transcriptional regulation by methyltransferases and their role in the heart: highlighting novel emerging functionality.
Szulik MW, Davis K, Bakhtina A, Azarcon P, Bia R, Horiuchi E, Franklin S.
Szulik MW, et al.
Am J Physiol Heart Circ Physiol. 2020 Oct 1;319(4):H847-H865. doi: 10.1152/ajpheart.00382.2020. Epub 2020 Aug 21.
Am J Physiol Heart Circ Physiol. 2020.
PMID: 32822544
Free PMC article.
Review.
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The chromatin-binding protein Smyd1 restricts adult mammalian heart growth.
Franklin S, Kimball T, Rasmussen TL, Rosa-Garrido M, Chen H, Tran T, Miller MR, Gray R, Jiang S, Ren S, Wang Y, Tucker HO, Vondriska TM.
Franklin S, et al.
Am J Physiol Heart Circ Physiol. 2016 Nov 1;311(5):H1234-H1247. doi: 10.1152/ajpheart.00235.2016. Epub 2016 Sep 23.
Am J Physiol Heart Circ Physiol. 2016.
PMID: 27663768
Free PMC article.
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Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart.
Warren JS, Tracy CM, Miller MR, Makaju A, Szulik MW, Oka SI, Yuzyuk TN, Cox JE, Kumar A, Lozier BK, Wang L, Llana JG, Sabry AD, Cawley KM, Barton DW, Han YH, Boudina S, Fiehn O, Tucker HO, Zaitsev AV, Franklin S.
Warren JS, et al.
Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7871-E7880. doi: 10.1073/pnas.1800680115. Epub 2018 Jul 30.
Proc Natl Acad Sci U S A. 2018.
PMID: 30061404
Free PMC article.
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The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis.
Sato M, Kadomatsu T, Miyata K, Warren JS, Tian Z, Zhu S, Horiguchi H, Makaju A, Bakhtina A, Morinaga J, Sugizaki T, Hirashima K, Yoshinobu K, Imasaka M, Araki M, Komohara Y, Wakayama T, Nakagawa S, Franklin S, Node K, Araki K, Oike Y.
Sato M, et al.
Nat Commun. 2021 May 5;12(1):2529. doi: 10.1038/s41467-021-22735-7.
Nat Commun. 2021.
PMID: 33953175
Free PMC article.
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The Smyd Family of Methyltransferases: Role in Cardiac and Skeletal Muscle Physiology and Pathology.
Tracy C, Warren JS, Szulik M, Wang L, Garcia J, Makaju A, Russell K, Miller M, Franklin S.
Tracy C, et al.
Curr Opin Physiol. 2018 Feb;1:140-152. doi: 10.1016/j.cophys.2017.10.001. Epub 2017 Dec 13.
Curr Opin Physiol. 2018.
PMID: 29435515
Free PMC article.
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