R01 GM126421/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2018	4
2019	3
2020	9
2021	6
2022	4
2023	6
2024	1

1

CARM1 regulates replication fork speed and stress response by stimulating PARP1.

Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, Poirier GG, Zou L. Genois MM, et al. Mol Cell. 2021 Feb 18;81(4):784-800.e8. doi: 10.1016/j.molcel.2020.12.010. Epub 2021 Jan 6. Mol Cell. 2021. PMID: 33412112 Free PMC article.

2

Effectors and effects of arginine methylation.

Wang Y, Bedford MT. Wang Y, et al. Biochem Soc Trans. 2023 Apr 26;51(2):725-734. doi: 10.1042/BST20221147. Biochem Soc Trans. 2023. PMID: 37013969 Free PMC article.

3

CARM1 arginine methyltransferase as a therapeutic target for cancer.

Santos M, Hwang JW, Bedford MT. Santos M, et al. J Biol Chem. 2023 Sep;299(9):105124. doi: 10.1016/j.jbc.2023.105124. Epub 2023 Aug 1. J Biol Chem. 2023. PMID: 37536629 Free PMC article. Review.

4

A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.

Liu Y, Iqbal A, Li W, Ni Z, Wang Y, Ramprasad J, Abraham KJ, Zhang M, Zhao DY, Qin S, Loppnau P, Jiang H, Guo X, Brown PJ, Zhen X, Xu G, Mekhail K, Ji X, Bedford MT, Greenblatt JF, Min J. Liu Y, et al. Nat Commun. 2022 Sep 16;13(1):5453. doi: 10.1038/s41467-022-33229-5. Nat Commun. 2022. PMID: 36114190 Free PMC article.

5

Screening for histone codebreakers.

Bedford MT. Bedford MT. J Biol Chem. 2018 Aug 31;293(35):13766-13767. doi: 10.1074/jbc.H118.005132. J Biol Chem. 2018. PMID: 30171150 Free PMC article.

6

The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer.

Gao G, Hausmann S, Flores NM, Benitez AM, Shen J, Yang X, Person MD, Gayatri S, Cheng D, Lu Y, Liu B, Mazur PK, Bedford MT. Gao G, et al. Nat Commun. 2023 Jan 23;14(1):363. doi: 10.1038/s41467-023-35864-y. Nat Commun. 2023. PMID: 36690626 Free PMC article.

7

CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth.

Yin S, Liu L, Ball LE, Wang Y, Bedford MT, Duncan SA, Wang H, Gan W. Yin S, et al. Cell Rep. 2023 Apr 25;42(4):112316. doi: 10.1016/j.celrep.2023.112316. Epub 2023 Mar 29. Cell Rep. 2023. PMID: 36995937 Free PMC article.

8

The Role of the PRMT5-SND1 Axis in Hepatocellular Carcinoma.

Wright T, Wang Y, Bedford MT. Wright T, et al. Epigenomes. 2021 Mar;5(1):2. doi: 10.3390/epigenomes5010002. Epub 2021 Jan 5. Epigenomes. 2021. PMID: 33768972 Free PMC article.

9

Pan-methylarginine antibody generation using PEG linked GAR motifs as antigens.

Wang Y, Person MD, Bedford MT. Wang Y, et al. Methods. 2022 Apr;200:80-86. doi: 10.1016/j.ymeth.2021.06.005. Epub 2021 Jun 6. Methods. 2022. PMID: 34107353 Free PMC article.

10

Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases.

Maron MI, Lehman SM, Gayatri S, DeAngelo JD, Hegde S, Lorton BM, Sun Y, Bai DL, Sidoli S, Gupta V, Marunde MR, Bone JR, Sun ZW, Bedford MT, Shabanowitz J, Chen H, Hunt DF, Shechter D. Maron MI, et al. iScience. 2021 Aug 11;24(9):102971. doi: 10.1016/j.isci.2021.102971. eCollection 2021 Sep 24. iScience. 2021. PMID: 34505004 Free PMC article.

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