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Page 1
Conformational elasticity can facilitate TALE-DNA recognition.
Lei H, Sun J, Baldwin EP, Segal DJ, Duan Y. Lei H, et al. Adv Protein Chem Struct Biol. 2014;94:347-64. doi: 10.1016/B978-0-12-800168-4.00009-3. Adv Protein Chem Struct Biol. 2014. PMID: 24629191 Free PMC article. Review.
How specific is CRISPR/Cas9 really?
O'Geen H, Yu AS, Segal DJ. O'Geen H, et al. Curr Opin Chem Biol. 2015 Dec;29:72-8. doi: 10.1016/j.cbpa.2015.10.001. Epub 2015 Oct 24. Curr Opin Chem Biol. 2015. PMID: 26517564 Free PMC article. Review.
Genome engineering at the dawn of the golden age.
Segal DJ, Meckler JF. Segal DJ, et al. Annu Rev Genomics Hum Genet. 2013;14:135-58. doi: 10.1146/annurev-genom-091212-153435. Epub 2013 May 20. Annu Rev Genomics Hum Genet. 2013. PMID: 23701416 Review.
Allele-Specific Reduction of the Mutant Huntingtin Allele Using Transcription Activator-Like Effectors in Human Huntington's Disease Fibroblasts.
Fink KD, Deng P, Gutierrez J, Anderson JS, Torrest A, Komarla A, Kalomoiris S, Cary W, Anderson JD, Gruenloh W, Duffy A, Tempkin T, Annett G, Wheelock V, Segal DJ, Nolta JA. Fink KD, et al. Cell Transplant. 2016;25(4):677-86. doi: 10.3727/096368916X690863. Epub 2016 Feb 4. Cell Transplant. 2016. PMID: 26850319 Free PMC article.