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Cytotoxic sigma-2 ligands trigger cancer cell death via cholesterol-induced-ER-stress.
Cell Death Dis. 2024 May 2;15(5):309. doi: 10.1038/s41419-024-06693-8.
Cell Death Dis. 2024.
PMID: 38697978
Free PMC article.
The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer.
Hagi T, Vangveravong S, Takchi R, Gong Q, Goedegebuure SP, Tiriac H, Van Tine BA, Powell MA, Hawkins WG, Spitzer D.
Hagi T, et al.
Sci Rep. 2024 Mar 16;14(1):6373. doi: 10.1038/s41598-024-56928-z.
Sci Rep. 2024.
PMID: 38493257
Free PMC article.
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